Bioanalytical effect-balance model to determine the bioavailability of organic contaminants in sediments affected by black and natural carbon

Braunig, Jennifer, Tang, Janet Y.M., Warne, Michael St. J. and Escher, Beate I. (2016) Bioanalytical effect-balance model to determine the bioavailability of organic contaminants in sediments affected by black and natural carbon. Chemosphere, 156 181-190. doi:10.1016/j.chemosphere.2016.04.056


Author Braunig, Jennifer
Tang, Janet Y.M.
Warne, Michael St. J.
Escher, Beate I.
Title Bioanalytical effect-balance model to determine the bioavailability of organic contaminants in sediments affected by black and natural carbon
Journal name Chemosphere   Check publisher's open access policy
ISSN 1879-1298
0045-6535
Publication date 2016-08-01
Year available 2016
Sub-type Article (original research)
DOI 10.1016/j.chemosphere.2016.04.056
Open Access Status Not Open Access
Volume 156
Start page 181
End page 190
Total pages 10
Place of publication Kidlington, Oxford, United Kingdom
Publisher Pergamon Press
Collection year 2017
Language eng
Formatted abstract
In sediments several binding phases dictate the fate and bioavailability of organic contaminants. Black carbon (BC) has a high sorptive capacity for organic contaminants and can limit their bioavailability, while the fraction bound to organic carbon (OC) is considered to be readily desorbable and bioavailable. We investigated the bioavailability and mixture toxicity of sediment-associated contaminants by combining different extraction techniques with in vitro bioanalytical tools. Sediments from a harbour with high fraction of BC, and sediments from remote, agricultural and urban areas with lower BC were treated with exhaustive solvent extraction, Tenax extraction and passive sampling to estimate total, bioaccessible and bioavailable fractions, respectively. The extracts were characterized with cell-based bioassays that measure dioxin-like activity (AhR-CAFLUX) and the adaptive stress response to oxidative stress (AREc32). Resulting bioanalytical equivalents, which are effect-scaled concentrations, were applied in an effect-balance model, consistent with a mass balance-partitioning model for single chemicals. Sediments containing BC had most of the bioactivity associated to the BC fraction, while the OC fraction played a role for sediments with lower BC. As effect-based sediment-water distribution ratios demonstrated, most of the bioactivity in the AhR-CAFLUX was attributable to hydrophobic chemicals while more hydrophilic chemicals activated AREc32, even though bioanalytical equivalents in the aqueous phase remained negligible. This approach can be used to understand the fate and effects of mixtures of diverse organic contaminants in sediments that would not be possible if single chemicals were targeted by chemical analysis; and make informed risk-based decisions concerning the management of contaminated sediments.
Keyword Bioavailability
Black carbon
Equilibrium passive sampling
In vitro bioassays
Mixture effect
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
National Research Centre for Environmental Toxicology Publications
 
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