Early parenting practices can significantly impact a child's development. Additionally, child behaviour influences parenting practices, especially in parents of children with ASD. There have been mixed findings regarding predictors of parenting practices among parents of children with ASD. This study aimed to assess whether parents of children with ASD and parents of typically developing children experience differences in parenting. This study also investigated whether child behavioural and emotional problems, perceived levels of support, parenting efficacy, adjustment, and family relationships predicted parental consistency, coercive parenting, positive encouragement, and parent-child relationships in parents of children with ASD. Using the My Say (N = 298) and IPS (N = 525) datasets, independent samples t-tests were run to compare the two parenting groups and hierarchical multiple regressions were run to assess predictors of parenting practices for My Say participants. The two samples differed significantly in their parenting practices. As predicted, parent adjustment and varying child behaviours significantly predicted coercive parenting and quality of parent-child relationship, prosocial child behaviour predicted use of positive encouragement, and parent teamwork significantly predicted parental consistency. Also as predicted, parents of children with ASD reported worse parenting factors and practices than parents of typically-developing children. Reasons for these patterns are discussed. Offering partial support for hypotheses, these findings expand on current literature regarding the influence of parent and child factors on parenting practices, and offer tentative support for the idea that there are possibly fewer key factors in determining parenting practices than previously anticipated. Findings can be applied in forming parenting program content and catering to specific needs of families with a child with ASD, while taking into consideration parenting attitudes, child behaviours, and other family characteristics.