Coronavirus infection and diversity in bats in the Australasian region

Smith, C. S., de Jong, C. E., Meers, J., Henning, J., Wang, L. -F. and Field, H. E. (2016) Coronavirus infection and diversity in bats in the Australasian region. EcoHealth, 13 1: 72-82. doi:10.1007/s10393-016-1116-x


Author Smith, C. S.
de Jong, C. E.
Meers, J.
Henning, J.
Wang, L. -F.
Field, H. E.
Title Coronavirus infection and diversity in bats in the Australasian region
Journal name EcoHealth   Check publisher's open access policy
ISSN 1612-9210
1612-9202
Publication date 2016-03
Year available 2016
Sub-type Article (original research)
DOI 10.1007/s10393-016-1116-x
Open Access Status Not Open Access
Volume 13
Issue 1
Start page 72
End page 82
Total pages 11
Place of publication New York, NY, United States
Publisher Springer New York LLC
Collection year 2017
Language eng
Formatted abstract
Following the SARS outbreak, extensive surveillance was undertaken globally to detect and identify coronavirus diversity in bats. This study sought to identify the diversity and prevalence of coronaviruses in bats in the Australasian region. We identified four different genotypes of coronavirus, three of which (an alphacoronavirus and two betacoronaviruses) are potentially new species, having less than 90% nucleotide sequence identity with the most closely related described viruses. We did not detect any SARS-like betacoronaviruses, despite targeting rhinolophid bats, the putative natural host taxa. Our findings support the virus-host co-evolution hypothesis, with the detection of Miniopterus bat coronavirus HKU8 (previously reported in Miniopterus species in China, Hong Kong and Bulgaria) in Australian Miniopterus species. Similarly, we detected a novel betacoronavirus genotype from Pteropus alecto which is most closely related to Bat coronavirus HKU9 identified in other pteropodid bats in China, Kenya and the Philippines. We also detected possible cross-species transmission of bat coronaviruses, and the apparent enteric tropism of these viruses. Thus, our findings are consistent with a scenario wherein the current diversity and host specificity of coronaviruses reflects co-evolution with the occasional host shift.
Keyword Asia
Australia
Bat
Coronavirus
Diversity
SARS
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Veterinary Science Publications
 
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