Resting state functional connectivity data supports detection of cognition in the rodent brain

Nasrallah, Fatima A., To, Xuan Vinh, Chen, Der-Yow, Routtenberg, Aryeh and Chuang, Kai-Hsiang (2016) Resting state functional connectivity data supports detection of cognition in the rodent brain. Data in Brief, 7 1156-1164. doi:10.1016/j.dib.2016.03.041


Author Nasrallah, Fatima A.
To, Xuan Vinh
Chen, Der-Yow
Routtenberg, Aryeh
Chuang, Kai-Hsiang
Title Resting state functional connectivity data supports detection of cognition in the rodent brain
Journal name Data in Brief   Check publisher's open access policy
ISSN 2352-3409
Publication date 2016-06-01
Year available 2016
Sub-type Article (original research)
DOI 10.1016/j.dib.2016.03.041
Open Access Status DOI
Volume 7
Start page 1156
End page 1164
Total pages 9
Place of publication Amsterdam, Netherlands
Publisher Elsevier BV
Collection year 2017
Language eng
Abstract Learning is a process which induces plastic changes in the synapses and connections across different regions of the brain. It is hypothesized that these new connections can be tracked with resting state functional connectivity MRI. While most of the evidence of learning-induced plasticity arises from previous human data, data from sedated rats that had undergone training for either 1 day or 5 days in a Morris Watermaze is presented. Seed points were taken from the somatosensory and visual cortices, and the hippocampal CA3 to detect connectivity changes. The data demonstrates that 5-day trained rats showed increased correlations between the hippocampal CA3 and thalamus, septum and cingulate cortex, compared to swim control or naïve animals. Seven days after the training, persistent but reorganized networks toward the cortex were observed. Data from the 1-day trained rats, on the contrary, showed connectivity similar to the swim control and less persistent. The connectivity in several regions was highly correlated with the behavioral performance in these animals. The data demonstrates that longitudinal changes following learning-induced plasticity can be detected and tracked with resting state connectivity
Keyword Functional connectivity
Learning and memory
Morris water maze
MRI
Neural plasticity
Resting state
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
Queensland Brain Institute Publications
 
Versions
Version Filter Type
Citation counts: Scopus Citation Count Cited 1 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 03 May 2016, 00:18:03 EST by System User on behalf of Learning and Research Services (UQ Library)