Indigenous Australians with non-small cell lung cancer or cervical cancer receive suboptimal treatment

Whop, Lisa J., Bernardes, Christina M., Kondalsamy-Chennakesavan, Srinivas, Darshan, Deepak, Chetty, Naven, Moore, Suzanne, Garvey, Gail, Walpole, Euan, Baade, Peter and Valery, Patricia C. (2016) Indigenous Australians with non-small cell lung cancer or cervical cancer receive suboptimal treatment. Asia-Pacific Journal of Clinical Oncology, . doi:10.1111/ajco.12463


Author Whop, Lisa J.
Bernardes, Christina M.
Kondalsamy-Chennakesavan, Srinivas
Darshan, Deepak
Chetty, Naven
Moore, Suzanne
Garvey, Gail
Walpole, Euan
Baade, Peter
Valery, Patricia C.
Title Indigenous Australians with non-small cell lung cancer or cervical cancer receive suboptimal treatment
Journal name Asia-Pacific Journal of Clinical Oncology   Check publisher's open access policy
ISSN 1743-7563
1743-7555
Publication date 2016-03-21
Year available 2016
Sub-type Article (original research)
DOI 10.1111/ajco.12463
Open Access Status Not Open Access
Total pages 8
Place of publication Chichester, West Sussex, United Kingdom
Publisher Wiley-Blackwell Publishing
Collection year 2017
Language eng
Formatted abstract
Background: Lung cancer and cervical cancer are higher in incidence for Indigenous Australians and survival is worse compared with non-Indigenous Australians. Here we aim to determine if being Indigenous and/or other factors are associated with patients receiving "suboptimal treatment" compared to "optimal treatment" according to clinical guidelines for two cancer types.

Methods: Data were collected from hospital medical records for Indigenous adults diagnosed with cervical cancer and non-small cell lung cancer (NSCLC) and a frequency-matched comparison group of non-Indigenous patients in the Queensland Cancer Registry between January 1998 and December 2004. The two cancer types were analyzed separately.

Results: A total of 105 women with cervical cancer were included in the study, 56 of whom were Indigenous. Indigenous women had higher odds of not receiving optimal treatment according to clinical guidelines (unadjusted OR 7.1; 95% CI, 1.5-33.3), even after adjusting for stage (OR 5.7; 95% CI, 1.2-27.3). Of 225 patients with NSCLC, 198 patients (56% Indigenous) had sufficient information available to be analyzed. The odds of receiving suboptimal treatment were significantly higher for Indigenous compared to non-Indigenous NSCLC patients (unadjusted OR 1.9; 95% CI, 1.0-3.6) and remained significant after adjusting for stage, comorbidity and age (adjusted OR 2.1; 95% CI, 1.1-4.1).

Conclusions: The monitoring of treatment patterns and appraisal against guidelines can provide valuable evidence of inequity in cancer treatment. We found that Indigenous people with lung cancer or cervical cancer received suboptimal treatment, reinforcing the need for urgent action to reduce the impact of these two cancer types on Indigenous people.
Keyword Cervical cancer
Clinical guidelines
Concordance
Indigenous Australians
Lung cancer
Treatment
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
Admin Only - School of Medicine
School of Medicine Publications
 
Versions
Version Filter Type
Citation counts: Scopus Citation Count Cited 0 times in Scopus Article
Google Scholar Search Google Scholar
Created: Tue, 26 Apr 2016, 02:21:40 EST by System User on behalf of Learning and Research Services (UQ Library)