An assessment of margins after lumpectomy in breast cancer management

Rivere, Amy E., Chiasson, Katherine F., Corsetti, Ralph L. and Fuhrman, George M. (2016) An assessment of margins after lumpectomy in breast cancer management. American Surgeon, 82 2: 156-160.

Author Rivere, Amy E.
Chiasson, Katherine F.
Corsetti, Ralph L.
Fuhrman, George M.
Title An assessment of margins after lumpectomy in breast cancer management
Journal name American Surgeon   Check publisher's open access policy
ISSN 0003-1348
Publication date 2016-02
Year available 2016
Sub-type Article (original research)
Open Access Status Not yet assessed
Volume 82
Issue 2
Start page 156
End page 160
Total pages 5
Place of publication Cumming, GA United States
Publisher Southeastern Surgical Congress
Collection year 2017
Language eng
Abstract We performed this study to evaluate our indications for margin re-excision (MRE) in the management of cancer patients opting for breast conservation therapy (BCT). We identified patients choosing breast conservation therapy from January 2012 to May 2014. Margins were considered negative if >2mm, close if <2 mm, and positive if ink was detected abutting tumor. Patients with close and positive margins underwent MRE. We identified 247 patients of which 190 had negative margins and did not require MRE, 46 patients had a close margin, and 11 had a positive margin, leading to an MRE rate of 23 per cent (57 of 247). The following variables were evaluated: tumor size, stage, estrogen receptor, progesterone receptor, HER2/neu receptor, and node status. None predicted the presence of tumor in the MRE specimen (P > 0.05). Patients with close margins had a 6.5 per cent (3 of 46), and patients with positive margins had a 36.4 per cent (4 of 11) incidence of tumor in the MRE specimens; this difference was statistically significant (P = 0.02). The low rate of finding tumor in MRE specimens of patients with close margins after lumpectomy for breast carcinoma argues for limiting MRE to patients with positive margins (ink on tumor) only. We have adopted this approach in our institution.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

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Sub-type: Article (original research)
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