Treatment of patients with multiple myeloma who are not eligible for stem cell transplantation: Position statement of the myeloma foundation of Australia Medical and Scientific Advisory Group

Quach, H., Joshua, D., Ho, J., Szer, J., Spencer, A., Harrison, S., Mollee, P., Roberts, A. W., Horvath, N., Talaulikar, D., To, B., Zannettino, A., Brown, R., Catley, L., Augustson, B., Jaksic, W., Gibson, J. and Prince, H. M. (2015) Treatment of patients with multiple myeloma who are not eligible for stem cell transplantation: Position statement of the myeloma foundation of Australia Medical and Scientific Advisory Group. Internal Medicine Journal, 45 3: 335-343. doi:10.1111/imj.12688


Author Quach, H.
Joshua, D.
Ho, J.
Szer, J.
Spencer, A.
Harrison, S.
Mollee, P.
Roberts, A. W.
Horvath, N.
Talaulikar, D.
To, B.
Zannettino, A.
Brown, R.
Catley, L.
Augustson, B.
Jaksic, W.
Gibson, J.
Prince, H. M.
Title Treatment of patients with multiple myeloma who are not eligible for stem cell transplantation: Position statement of the myeloma foundation of Australia Medical and Scientific Advisory Group
Journal name Internal Medicine Journal   Check publisher's open access policy
ISSN 1445-5994
1444-0903
Publication date 2015-03
Sub-type Article (original research)
DOI 10.1111/imj.12688
Open Access Status Not Open Access
Volume 45
Issue 3
Start page 335
End page 343
Total pages 9
Place of publication Richmond, VIC, Australia
Publisher Blackwell Publishing
Collection year 2016
Language eng
Abstract Options for treatment of elderly patients with multiple myeloma have expanded substantially following the development of immunomodulatory drugs (IMiD), proteasome inhibitors and with enhancement in safety of high-dose therapy and autologous stem cell transplant (HDT + ASCT). The recognition of biological heterogeneity among elderly patients has made delivery of therapy more challenging. An individualised approach to treatment selection is recommended in an era in which highly efficacious treatment options are available for transplant-ineligible patients. Here, we summarise recommendations for patients who are considered unsuitable for HDT + ASCT, including pretreatment considerations, and induction, maintenance and supportive care therapies.
Keyword Elderly
Multiple myeloma
Therapy
Transplant ineligible
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Medicine Publications
 
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Created: Thu, 31 Mar 2016, 15:16:37 EST by Kristen Gibbons on behalf of Learning and Research Services (UQ Library)