The hitchhiker's guide to Europe: the infection dynamics of an ongoing Wolbachia invasion and mitochondrial selective sweep in Rhagoletis cerasi

Schuler, Hannes, Koppler, Kirsten, Daxbock-Horvath, Sabine, Rasool, Bilal, Krumbock, Susanne, Schwarz, Dietmar, Hoffmeister, Thomas S., Schlick-Steiner, Birgit C., Steiner, Florian M., Telschow, Arndt, Stauffer, Christian, Arthofer, Wolfgang and Riegler, Markus (2016) The hitchhiker's guide to Europe: the infection dynamics of an ongoing Wolbachia invasion and mitochondrial selective sweep in Rhagoletis cerasi. Molecular Ecology, 25 7: 1595-1609. doi:10.1111/mec.13571


Author Schuler, Hannes
Koppler, Kirsten
Daxbock-Horvath, Sabine
Rasool, Bilal
Krumbock, Susanne
Schwarz, Dietmar
Hoffmeister, Thomas S.
Schlick-Steiner, Birgit C.
Steiner, Florian M.
Telschow, Arndt
Stauffer, Christian
Arthofer, Wolfgang
Riegler, Markus
Title The hitchhiker's guide to Europe: the infection dynamics of an ongoing Wolbachia invasion and mitochondrial selective sweep in Rhagoletis cerasi
Formatted title
The hitchhiker's guide to Europe: the infection dynamics of an ongoing Wolbachia invasion and mitochondrial selective sweep in Rhagoletis cerasi
Journal name Molecular Ecology   Check publisher's open access policy
ISSN 1365-294X
0962-1083
Publication date 2016-03-15
Year available 2016
Sub-type Article (original research)
DOI 10.1111/mec.13571
Open Access Status DOI
Volume 25
Issue 7
Start page 1595
End page 1609
Total pages 15
Place of publication Chichester, West Sussex, United Kingdom
Publisher Wiley-Blackwell Publishing
Collection year 2017
Language eng
Formatted abstract
Wolbachia is a maternally inherited and ubiquitous endosymbiont of insects. It can hijack host reproduction by manipulations such as cytoplasmic incompatibility (CI) to enhance vertical transmission. Horizontal transmission of Wolbachia can also result in the colonization of new mitochondrial lineages. In this study, we present a 15-year-long survey of Wolbachia in the cherry fruit fly Rhagoletis cerasi across Europe and the spatiotemporal distribution of two prevalent strains, wCer1 and wCer2, and associated mitochondrial haplotypes in Germany. Across most of Europe, populations consisted of either 100% singly (wCer1) infected individuals with haplotype HT1, or 100% doubly (wCer1&2) infected individuals with haplotype HT2, differentiated only by a single nucleotide polymorphism. In central Germany, singly infected populations were surrounded by transitional populations, consisting of both singly and doubly infected individuals, sandwiched between populations fixed for wCer1&2. Populations with fixed infection status showed perfect association of infection and mitochondria, suggesting a recent CI-driven selective sweep of wCer2 linked with HT2. Spatial analysis revealed a range expansion for wCer2 and a large transition zone in which wCer2 splashes appeared to coalesce into doubly infected populations. Unexpectedly, the transition zone contained a large proportion (22%) of wCer1&2 individuals with HT1, suggesting frequent intraspecific horizontal transmission. However, this horizontal transmission did not break the strict association between infection types and haplotypes in populations outside the transition zone, suggesting that this horizontally acquired Wolbachia infection may be transient. Our study provides new insights into the rarely studied Wolbachia invasion dynamics in field populations.
Keyword Endosymbiont
Horizontal transmission
Infection dynamics
Modelling
Selective sweep
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Biological Sciences Publications
 
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