Efficacy of some colloidal silver preparations and silver salts against Proteus bacteria, one possible cause of rheumatoid arthritis

Disaanayake, D. M. B. T., Faoagali, Joan, Laroo, Hans, Hancock, Gerald and Whitehouse, Michael (2014) Efficacy of some colloidal silver preparations and silver salts against Proteus bacteria, one possible cause of rheumatoid arthritis. Inflammopharmacology, 22 2: 73-77. doi:10.1007/s10787-013-0198-0


Author Disaanayake, D. M. B. T.
Faoagali, Joan
Laroo, Hans
Hancock, Gerald
Whitehouse, Michael
Title Efficacy of some colloidal silver preparations and silver salts against Proteus bacteria, one possible cause of rheumatoid arthritis
Formatted title
Efficacy of some colloidal silver preparations and silver salts against Proteus bacteria, one possible cause of rheumatoid arthritis
Journal name Inflammopharmacology   Check publisher's open access policy
ISSN 1568-5608
0925-4692
Publication date 2014-04
Year available 2014
Sub-type Letter to editor, brief commentary or brief communication
DOI 10.1007/s10787-013-0198-0
Open Access Status Not yet assessed
Volume 22
Issue 2
Start page 73
End page 77
Total pages 5
Place of publication Basel, Switzerland
Publisher Springer Basel AG
Language eng
Formatted abstract
There has been increased interest in the role of anti-Proteus antibodies in the aetiology of rheumatoid arthritis (RA) and whether chemotherapeutic agents active against Proteus species might reduce the risk and/or exacerbations of RA. We examined the in vitro antibacterial effects of ten different silver preparations which were either ionic silver [Ag(I)] solutions or nanoparticulate silver (NPS) (Ag0) suspensions against ATCC and two wild (clinical) strains of Proteus. The data establish the low minimum inhibitory concentration and minimum bactericidal concentration of all the silver formulations tested against these four Proteus strains. In a pilot study, a potent NPS preparation ex vivo showed long-lasting anti-Proteus activity in a normal human volunteer.
Keyword Nanoparticulate silver
Proteus
Rheumatoid arthritis
Silver antimicrobials
Q-Index Code CX
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Letter to editor, brief commentary or brief communication
Collection: School of Biomedical Sciences Publications
 
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