Marine bioactive compounds and health promoting perspectives; innovation pathways for drug discovery

Suleria, Hafiz Ansar Rasul, Gobe, Glenda, Masci, Paul and Osborne, Simone A. (2016) Marine bioactive compounds and health promoting perspectives; innovation pathways for drug discovery. Trends in Food Science and Technology, 50 44-55. doi:10.1016/j.tifs.2016.01.019


Author Suleria, Hafiz Ansar Rasul
Gobe, Glenda
Masci, Paul
Osborne, Simone A.
Title Marine bioactive compounds and health promoting perspectives; innovation pathways for drug discovery
Journal name Trends in Food Science and Technology   Check publisher's open access policy
ISSN 0924-2244
1879-3053
Publication date 2016-04-01
Year available 2016
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.tifs.2016.01.019
Open Access Status Not Open Access
Volume 50
Start page 44
End page 55
Total pages 12
Place of publication Kidlington, Oxford, United Kingdom
Publisher Pergamon Press
Collection year 2017
Language eng
Formatted abstract
Background: Marine organisms are one of the most important sources of bioactive compounds for the food and pharmaceutical industries. Bioactive compounds can be isolated from various sources including marine plants, animals and microorganisms.

Scope and approach: Marine bioactive compounds exhibit significant and biological properties contributing to their nutraceutical and pharmaceutical potential and are also considered to be safer alternatives to some existing synthetic drugs. As such, some marine bioactive compounds are currently under investigation at an advanced stage of clinical trials with a few of them already being marketed as safer drugs.

Key findings and conclusions: Marine bioactive compounds that have been the most extensively studied include carbohydrates, pigments, polyphenols, peptides, proteins and essential fatty acids. These compounds have rheological properties, deeming them useful in the food industry, as well as various biological functions like anti-oxidant, anti-thrombotic, anti-coagulant, anti-inflammatory, anti-proliferative, anti-hypertensive, anti-diabetic and cardio-protection activities making them attractive nutraceuticals and pharmaceutical compounds. This review summarises current research on bioactive compounds from different marine sources and brings into focus the potential use of these compounds in the food industry and in drug discovery to treat and prevent various chronic diseases.
Keyword Drug discovery
Health perspectives
Marine bioactive compounds
Nutraceuticals
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: HERDC Pre-Audit
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