Economic evaluation of a psychological intervention for high distress cancer patients and carers: Costs and quality-adjusted life years

Chatterton, Mary Lou, Chambers, Suzanne, Occhipinti, Stefano, Girgis, Afaf, Dunn, Jeffrey, Carter, Rob, Shih, Sophy and Mihalopoulos, Cathrine (2015) Economic evaluation of a psychological intervention for high distress cancer patients and carers: Costs and quality-adjusted life years. Psycho-Oncology, 25 7: 857-864. doi:10.1002/pon.4020


Author Chatterton, Mary Lou
Chambers, Suzanne
Occhipinti, Stefano
Girgis, Afaf
Dunn, Jeffrey
Carter, Rob
Shih, Sophy
Mihalopoulos, Cathrine
Title Economic evaluation of a psychological intervention for high distress cancer patients and carers: Costs and quality-adjusted life years
Journal name Psycho-Oncology   Check publisher's open access policy
ISSN 1099-1611
Publication date 2015-01-01
Sub-type Article (original research)
DOI 10.1002/pon.4020
Volume 25
Issue 7
Start page 857
End page 864
Total pages 8
Place of publication West Sussex, United Kingdom
Publisher John Wiley and Sons
Collection year 2016
Language eng
Formatted abstract
Objective: This study compared the cost-effectiveness of a psychologist-led, individualised cognitivebehavioural intervention (PI) to a nurse-led, minimal contact self-management condition for highlydistressed cancer patients and carers.
Methods: This was an economic evaluation conducted alongside a randomised trial of highlydistressed adult cancer patients and carers calling cancer helplines. Services used by participants weremeasured using a resource use questionnaire, and quality-adjusted life years were measured using theassessment of quality of life – eight-dimension – instrument collected through a computer-assistedtelephone interview. The base case analysis stratified participants based on the baseline score on theBrief Symptom Inventory. Incremental cost-effectiveness ratio confidence intervals were calculatedwith a nonparametric bootstrap to reflect sampling uncertainty. The results were subjected to sensitiv-ity analysis by varying unit costs for resource use and the method for handling missing data.
Results: No significant differences were found in overall total costs or quality-adjusted life years(QALYs) between intervention groups. Bootstrapped data suggest the PI had a higher probabilityof lower cost and greater QALYs for both carers and patients with high distress at baseline. Forpatients with low levels of distress at baseline, the PI had a higher probability of greater QALYsbut at additional cost. Sensitivity analysis showed the results were robust.
Conclusions: The PI may be cost-effective compared with the nurse-led, minimal contact self-management condition for highly distressed cancer patients and carers. More intensive psychologicalintervention for patients with greater levels of distress appears warranted.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: UQ Centre for Clinical Research Publications
Official 2016 Collection
School of Social Science Publications
 
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Created: Tue, 08 Mar 2016, 23:46:58 EST by Matthew Lamb on behalf of School of Medicine