Phase contrast ultrashort TE: a more reliable technique for measurement of high-velocity turbulent stenotic jets

O'Brien, Kieran R., Myerson, Saul G., Cowan, Brett R., Young, Alistair A. and Robson, Matthew D. (2009) Phase contrast ultrashort TE: a more reliable technique for measurement of high-velocity turbulent stenotic jets. Magnetic Resonance in Medicine, 62 3: 626-636. doi:10.1002/mrm.22051


Author O'Brien, Kieran R.
Myerson, Saul G.
Cowan, Brett R.
Young, Alistair A.
Robson, Matthew D.
Title Phase contrast ultrashort TE: a more reliable technique for measurement of high-velocity turbulent stenotic jets
Journal name Magnetic Resonance in Medicine   Check publisher's open access policy
ISSN 0740-3194
1522-2594
Publication date 2009-09
Sub-type Article (original research)
DOI 10.1002/mrm.22051
Open Access Status Not yet assessed
Volume 62
Issue 3
Start page 626
End page 636
Total pages 11
Place of publication Hoboken, NJ, United States
Publisher John Wiley & Sons
Language eng
Abstract Accurate measurement of peak velocity is critical to the assessment of patients with stenotic valvular disease. Conventional phase contrast (PC) methods for imaging high-velocity jets in aortic stenosis are susceptible to intravoxel dephasing signal loss, which can result in unreliable measurements. The most effective method for reducing intravoxel dephasing is to shorten the echo time (TE); however, the amount that TE can be shortened in conventional sequences is limited. A new sequence incorporating velocity-dependent slice excitation and ultrashort TE (UTE) centric radial readout trajectories is proposed that reduces TE from 2.85 to 0.65 ms. In a high-velocity stenotic jet phantom, a conventional sequence had >5% flow error at a flow rate of only 400 mL/s (velocity >358 cm/s), whereas the PC-UTE showed excellent agreement (<5% error) at much higher flow rates (1080 mL/s, 965 cm/s). In vivo feasibility studies demonstrated that by measuring velocity over a shorter time the PC-UTE approach is more robust to intravoxel dephasing signal loss. It also has less inherent higher-order motion encoding. This sequence therefore demonstrates potential as a more robust method for measuring peak velocity and flow in high-velocity turbulent stenotic jets.
Keyword High-velocity
Phase contrast
Turbulent jets
Ultrashort TE
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Centre for Advanced Imaging Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 24 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 29 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Fri, 04 Mar 2016, 14:30:10 EST by System User on behalf of Learning and Research Services (UQ Library)