The effect of glucose and mental stress on cutaneous microvascular endothelial function

Brion, MJ and Drummond, PD (2005) The effect of glucose and mental stress on cutaneous microvascular endothelial function. Psychophysiology, 42 3: 282-289. doi:10.1111/j.1469-8986.2005.00284.x


Author Brion, MJ
Drummond, PD
Title The effect of glucose and mental stress on cutaneous microvascular endothelial function
Journal name Psychophysiology   Check publisher's open access policy
ISSN 0048-5772
Publication date 2005
Sub-type Article (original research)
DOI 10.1111/j.1469-8986.2005.00284.x
Volume 42
Issue 3
Start page 282
End page 289
Total pages 8
Language eng
Subject 1314 Physiology
2737 Physiology (medical)
3200 Psychology
3206 Neuropsychology and Physiological Psychology
3205 Experimental and Cognitive Psychology
Abstract Glucose and mental stress, independently, have been found to impair arterial endothelial function (an indicator of vascular health). The present study sought to determine whether the combination of glucose and stress would have a greater effect on microvascular endothelial function than each on its own. To assess endothelial function, surges in skin blood flow (reactive hyperemia), following the release of cuff pressure to the upper arm at 200 mmHg for 5 min, were measured with laser Doppler flowmetry in 40 young, healthy females. Endothelial function did not change significantly following a 5-min mathematics stressor or the consumption of 75 g of glucose. However, the combination of glucose and stress impaired endothelium-dependent dilatation 30 min after glucose consumption. These findings suggest that combinations of vascular risk factors may be more threatening to cardiovascular health than singularly occurring factors. Copyright
Keyword Endothelium
Glucose
Laser Doppler flowmetry
Mental stress
Reactive hyperemia
Skin blood flow
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
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