Inflammatory reaction to fish oil coated polypropylene mesh used for laparoscopic incisional hernia repair: a case report

Kong, Chia Yew, Lai, Lee Lee, Khoo, Amanda Yin Yen, Rahman, Nazarina Abdul and Chin, Kin Fah (2016) Inflammatory reaction to fish oil coated polypropylene mesh used for laparoscopic incisional hernia repair: a case report. BMC Surgery, 16 8: . doi:10.1186/s12893-016-0123-8


Author Kong, Chia Yew
Lai, Lee Lee
Khoo, Amanda Yin Yen
Rahman, Nazarina Abdul
Chin, Kin Fah
Title Inflammatory reaction to fish oil coated polypropylene mesh used for laparoscopic incisional hernia repair: a case report
Journal name BMC Surgery   Check publisher's open access policy
ISSN 1471-2482
Publication date 2016-02-11
Year available 2016
Sub-type Article (original research)
DOI 10.1186/s12893-016-0123-8
Open Access Status DOI
Volume 16
Issue 8
Total pages 6
Place of publication London, United Kingdom
Publisher BioMed Central
Collection year 2017
Language eng
Formatted abstract
Background: Polypropylene meshes are widely used in hernia repairs. Hernia meshes have been developed incorporating coatings of active agents. One commercially available mesh has a fish oil coating which is promoted as having anti-inflammatory properties. We report a case, a symptomatic foreign body granuloma reaction associated with a fish oil coated polypropylene mesh, which required eventual mesh explantation.

Case presentation: A 61-year old lady with previous peptic ulcer disease underwent a laparoscopic intraperitoneal placement of mesh for incisional hernia utilising a fish oil coated polypropylene mesh. The patient presented 3 months after the procedure complaining of dyspepsia and pain at the operative site. There was no discharge. The patient was managed conservatively. She presented 10 months post-operatively with progressively worsening symptoms and a hard palpable mass in the epigastrium. Abdominal laparoscopy revealed dense adhesive disease around the mesh with exudates. Adhesiolysis, mesh explantation and a partial gastrectomy was performed. Histopathological examination revealed a foreign body granuloma formation to the mesh.

Conclusion: In-vivo studies looking at intraperitoneal mesh placement with fish oil coatings including data on surgical outcomes such as fistula and adhesive characteristics are scarce in the literature. Further monitoring and studies are required to investigate the safety and efficacy profile of this mesh type in in-vivo models.
Keyword Fish oil coated hernia mesh
Hernia
Hernia mesh
Hernia repair complications
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
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