Nuclear organisation of some immunohistochemically identifiable neural systems in five species of insectivore-Crocidura cyanea, Crocidura olivieri, Sylvisorex ollula, Paraechinus aethiopicus and Atelerix frontalis

Calvey, Tanya, Patzke, Nina, Bennett, Nigel C., Consolate, Kaswera-Kyamaka, Gilissen, Emmanuel, Alagaili, Abdulaziz N., Mohammed, Osama B., Pettigrew, John D. and Manger, Paul R. (2016) Nuclear organisation of some immunohistochemically identifiable neural systems in five species of insectivore-Crocidura cyanea, Crocidura olivieri, Sylvisorex ollula, Paraechinus aethiopicus and Atelerix frontalis. Journal of Chemical Neuroanatomy, 72 34-52. doi:10.1016/j.jchemneu.2015.12.012


Author Calvey, Tanya
Patzke, Nina
Bennett, Nigel C.
Consolate, Kaswera-Kyamaka
Gilissen, Emmanuel
Alagaili, Abdulaziz N.
Mohammed, Osama B.
Pettigrew, John D.
Manger, Paul R.
Title Nuclear organisation of some immunohistochemically identifiable neural systems in five species of insectivore-Crocidura cyanea, Crocidura olivieri, Sylvisorex ollula, Paraechinus aethiopicus and Atelerix frontalis
Formatted title
Nuclear organisation of some immunohistochemically identifiable neural systems in five species of insectivore-Crocidura cyanea, Crocidura olivieri, Sylvisorex ollula, Paraechinus aethiopicus and Atelerix frontalis
Journal name Journal of Chemical Neuroanatomy   Check publisher's open access policy
ISSN 1873-6300
0891-0618
Publication date 2016-03-01
Year available 2015
Sub-type Article (original research)
DOI 10.1016/j.jchemneu.2015.12.012
Open Access Status Not Open Access
Volume 72
Start page 34
End page 52
Total pages 19
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Collection year 2016
Language eng
Abstract The organization of the cholinergic, catecholaminergic, and serotonergic neurons in the brains of five species of insectivores and the orexinergic (hypocretinergic) system in four insectivore species is presented. We aimed to investigate the nuclear complement of these neural systems in comparison to those of other mammalian species. Brains of insectivores were coronally sectioned and immunohistochemically stained with antibodies against choline acetyltransferase, tyrosine hydroxylase, serotonin and orexin-A. The majority of nuclei were similar among the species investigated and to mammals in general, but certain differences in the nuclear complement highlighted potential phylogenetic interrelationships. In the cholinergic system, the three shrew species lacked parabigeminal and Edinger–Westphal nuclei. In addition, the appearance of the laterodorsal tegmental nucleus in all insectivores revealed a mediodorsal arch. All three of these features are the same as those present in microchiropterans. The catecholaminergic system of the three shrew species lacked the A4 and A15d nuclei, as well as having an incipient A9v nucleus, again features found in microchiropteran brains. The serotonergic and orexinergic systems of the insectivores are similar to those seen across most eutherian mammals. The analysis of similarities and differences across mammalian species indicates a potential phylogenetic relationship between the Soricidae (shrews) and the microchiropterans.
Keyword Choline acetyltransferase
Tyrosine hydroxylase
Serotonin
Hypocretin
Orexin
Evolution
Mammal
Insectivora
Chiroptera
Neural systems
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Queensland Brain Institute Publications
Official 2016 Collection
 
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