Microfluidic Bioprinting of Heterogeneous 3D Tissue Constructs Using Low-Viscosity Bioink

Colosi, Cristina, Shin, Su Ryon, Manoharan, Vijayan, Massa, Solange, Costantini, Marco, Barbetta, Andrea, Dokmeci, Mehmet Remzi, Dentini, Mariella and Khademhosseini, Ali (2016) Microfluidic Bioprinting of Heterogeneous 3D Tissue Constructs Using Low-Viscosity Bioink. Advanced Materials, 28 4: 677-684a. doi:10.1002/adma.201503310


Author Colosi, Cristina
Shin, Su Ryon
Manoharan, Vijayan
Massa, Solange
Costantini, Marco
Barbetta, Andrea
Dokmeci, Mehmet Remzi
Dentini, Mariella
Khademhosseini, Ali
Title Microfluidic Bioprinting of Heterogeneous 3D Tissue Constructs Using Low-Viscosity Bioink
Journal name Advanced Materials   Check publisher's open access policy
ISSN 1521-4095
0935-9648
Publication date 2016-01-27
Sub-type Article (original research)
DOI 10.1002/adma.201503310
Open Access Status Not Open Access
Volume 28
Issue 4
Start page 677
End page 684a
Total pages 8
Place of publication Weinheim, Germany
Publisher Wiley
Collection year 2017
Abstract A novel bioink and a dispensing technique for 3D tissue-engineering applications are presented. The technique incorporates a coaxial extrusion needle using a low-viscosity cell-laden bioink to produce highly defined 3D biostructures. The extrusion system is then coupled to a microfluidic device to control the bioink arrangement deposition, demonstrating the versatility of the bioprinting technique. This low-viscosity cell-responsive bioink promotes cell migration and alignment within each fiber organizing the encapsulated cells.
Keyword 3D tissue engineering
Bioinks
Bioprinting
Microfluidics
Vascular tissue engineering
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
Australian Institute for Bioengineering and Nanotechnology Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 15 times in Thomson Reuters Web of Science Article | Citations
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Created: Fri, 26 Feb 2016, 10:56:44 EST by Anthony Yeates on behalf of Learning and Research Services (UQ Library)