Effect of pasteurisation on the concentrations of vitamin D compounds in donor breastmilk

Gomes, Fabio P., Shaw, P. Nicholas, Whitfield, Karen, Koorts, Pieter, McConachy, Helen and Hewavitharana, Amitha K. (2016) Effect of pasteurisation on the concentrations of vitamin D compounds in donor breastmilk. International Journal of Food Sciences and Nutrition, 67 1: 16-19. doi:10.3109/09637486.2015.1126566


Author Gomes, Fabio P.
Shaw, P. Nicholas
Whitfield, Karen
Koorts, Pieter
McConachy, Helen
Hewavitharana, Amitha K.
Title Effect of pasteurisation on the concentrations of vitamin D compounds in donor breastmilk
Journal name International Journal of Food Sciences and Nutrition   Check publisher's open access policy
ISSN 0963-7486
1465-3478
Publication date 2016-01-21
Sub-type Article (original research)
DOI 10.3109/09637486.2015.1126566
Open Access Status Not Open Access
Volume 67
Issue 1
Start page 16
End page 19
Total pages 4
Place of publication Abingdon, Oxfordshire, United Kingdom
Publisher Taylor & Francis
Collection year 2017
Language eng
Formatted abstract
Premature infants are the main recipients of pasteurised donor human milk (PDHM), when their mothers are unable to provide their own. In this study, we evaluated the effect of pasteurisation on the concentrations of vitamin D compounds in donor breastmilk. Milk samples were obtained pre- and post-Holder pasteurisation. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) was used to analyse the samples for vitamins D2 and D3 (D2 and D3) and 25-hydroxyvitamins D2 and D3 (25(OH)D2 and 25(OH)D3). The significance of differences in vitamin D concentrations between the two groups of milk samples was assessed using the Wilcoxon matched-pairs signed rank test, in which p < 0.05 was considered significant. Pasteurisation resulted in a significant reduction (p < 0.05) in the content of D2, D3, 25(OH)D2 and 25(OH)D3. The losses ranged from 10% to 20% following pasteurisation.
Keyword Bone disorders
Holder pasteurisation
Milk bank
Preterm infants
Tandem mass-spectrometry
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
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