Acquired resistance to immunotherapy and future challenges

Restifo, Nicholas R., Smyth, Mark J. and Snyder, Alexandra (2016) Acquired resistance to immunotherapy and future challenges. Nature Reviews Cancer, 16 2: 121-126. doi:10.1038/nrc.2016.2


Author Restifo, Nicholas R.
Smyth, Mark J.
Snyder, Alexandra
Title Acquired resistance to immunotherapy and future challenges
Journal name Nature Reviews Cancer   Check publisher's open access policy
ISSN 1474-1768
1474-175X
Publication date 2016-02
Year available 2016
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1038/nrc.2016.2
Open Access Status Not Open Access
Volume 16
Issue 2
Start page 121
End page 126
Total pages 6
Place of publication London, United Kingdom
Publisher Nature Publishing Group
Collection year 2017
Language eng
Abstract Advances in immunotherapy have resulted in remarkable clinical responses in some patients. However, one of the biggest challenges in cancer therapeutics is the development of resistant disease and disease progression on or after therapy. Given that many patients have now received various types of immunotherapy, we asked three scientists to give their views on the current evidence for whether acquired resistance to immunotherapy exists in patients and the future challenges posed by immunotherapy.
Keyword Cancer immunotherapy
Cancer therapeutic resistance
Immunotherapy
Resistance
Acquired resistance
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: HERDC Pre-Audit
Admin Only - School of Medicine
School of Medicine Publications
 
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