Origin and detection of neonatal seizures: animal and clinical studies

Bjorkman, S. Tracey (2016). Origin and detection of neonatal seizures: animal and clinical studies. In Walker, David W. (Ed.), Prenatal and postnatal determinants of development (pp. 343-358) New York, NY United States: Humana Press. doi:10.1007/978-1-4939-3014-2_17


Author Bjorkman, S. Tracey
Title of chapter Origin and detection of neonatal seizures: animal and clinical studies
Title of book Prenatal and postnatal determinants of development
Place of Publication New York, NY United States
Publisher Humana Press
Publication Year 2016
Sub-type Research book chapter (original research)
DOI 10.1007/978-1-4939-3014-2_17
Open Access Status Not Open Access
Year available 2016
Series Neuromethods
ISBN 9781493930135
9781493930142
ISSN 1940-6045
0893-2336
Editor Walker, David W.
Volume number 109
Chapter number 17
Start page 343
End page 358
Total pages 16
Total chapters 17
Collection year 2017
Language eng
Abstract/Summary Neonatal seizures remain a major clinical problem worldwide and are harmful to the developing brain. Seizures are associated with poor neurodevelopmental outcomes and significant risk of death requiring urgent diagnosis and intervention. Current antiepileptic drugs however have limited efficacy and are potentially harmful to the developing newborn brain. Despite this, standard clinical practice for the treatment of neonatal seizures remains unchanged. This chapter describes a clinically relevant neonatal animal model of HI-induced seizures.
Keyword Seizures
aEEG
Hypoxia-ischemia
Brain injury
Pig
Neonatal seizures
Q-Index Code B1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Book Chapter
Collections: UQ Centre for Clinical Research Publications
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