Genetic and environmental contributions to perceived intensity and pleasantness of androstenone odor: an international twin study

Knaapila, Antti, Tuorila, Hely, Silventoinen, Karri, Wright, Margaret J., Kyvik, Kirsten O., Cherkas, Lynn F., Keskitalo, Kaisu, Hansen, Jonathan, Martin, Nicholas G., Spector, Tim D., Kaprio, Jaakko and Perola, Markus (2008) Genetic and environmental contributions to perceived intensity and pleasantness of androstenone odor: an international twin study. Chemosensory Perception, 1 1: 34-42. doi:10.1007/s12078-007-9005-x


Author Knaapila, Antti
Tuorila, Hely
Silventoinen, Karri
Wright, Margaret J.
Kyvik, Kirsten O.
Cherkas, Lynn F.
Keskitalo, Kaisu
Hansen, Jonathan
Martin, Nicholas G.
Spector, Tim D.
Kaprio, Jaakko
Perola, Markus
Title Genetic and environmental contributions to perceived intensity and pleasantness of androstenone odor: an international twin study
Journal name Chemosensory Perception   Check publisher's open access policy
ISSN 1936-5810
1936-5802
Publication date 2008-03-01
Sub-type Article (original research)
DOI 10.1007/s12078-007-9005-x
Open Access Status Not yet assessed
Volume 1
Issue 1
Start page 34
End page 42
Total pages 9
Place of publication New York, NY, United States
Publisher Springer New York LLC
Language eng
Abstract We estimated the genetic and environmental components of variation in perceived intensity and pleasantness of androstenone, an odorous compound showing specific anosmia, by modeling twin data from Finland, Denmark, the UK, and Australia. The pooled data comprised 917 twin individuals (338 are male and 579 are female; aged from 10 to 83years) including 126 complete monozygous and 264 dizygous twin pairs as well as 137 twin individuals without their co-twin. They rated intensity and pleasantness of androstenone and citronellal (control) odors using nine categories. Additive genetic effects (heritability) contributed 28 and 21% to the variation in the perceived intensity and pleasantness of androstenone, respectively, but negligibly to variations in citronellal perception. A strong genetic correlation existed between the intensity and pleasantness of androstenone, whereas the environmental correlation was negligible. These results suggest that both intensity and pleasantness of androstenone are moderately influenced by genetic factors and that the traits are modified by an overlapping set of genes.
Keyword Heritability
Olfaction
Psychophysics
Scratch-and-sniff
Smell
Specific anosmia
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Queensland Brain Institute Publications
 
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