Comparative seroprevalence of Leptospira interrogans in Colombian mammals along a climatic gradient

González Astudillo, Viviana, Wehdeking Hernández, Dave, Peña Stadlin, Juliana, Arias Bernal, Leonardo, Lombo Rodríguez, Dora Adriana and Astudillo Hernández, Miryam (2012) Comparative seroprevalence of Leptospira interrogans in Colombian mammals along a climatic gradient. Journal of Zoo and Wildlife Medicine, 43 4: 768-775. doi:10.1638/2011-0103R2.1


Author González Astudillo, Viviana
Wehdeking Hernández, Dave
Peña Stadlin, Juliana
Arias Bernal, Leonardo
Lombo Rodríguez, Dora Adriana
Astudillo Hernández, Miryam
Title Comparative seroprevalence of Leptospira interrogans in Colombian mammals along a climatic gradient
Formatted title
Comparative seroprevalence of Leptospira interrogans in Colombian mammals along a climatic gradient
Journal name Journal of Zoo and Wildlife Medicine   Check publisher's open access policy
ISSN 1937-2825
1042-7260
Publication date 2012
Sub-type Article (original research)
DOI 10.1638/2011-0103R2.1
Open Access Status Not Open Access
Volume 43
Issue 4
Start page 768
End page 775
Total pages 8
Place of publication Yulee, FL, United States
Publisher American Association of Zoo Veterinarians
Language eng
Formatted abstract
Leptospirosis is a widespread zoonotic disease with well-established impacts on human health in tropical and subtropical regions. Although Leptospira spp. are known to readily infect many wildlife species, the understanding of interspecies and climatic variability in patterns of infection in Neotropical mammals is limited. To improve the understanding of this interplay, 85 mammals representing 17 species were sampled from four Colombian zoos along a climatic gradient. Prevalence of the 21 primary serovars against Leptospira interrogans was determined using the microagglutination test. Individuals were considered positive for a given serovar if antibodies were observable at a 1:100 dilution or greater. Overall prevalence was 9.52%, with positive titers to serovar hurstbridge in Carnivora (Canidae); serovar sarmin in Primata (Atelidae); and serovars australis, mini, autumnalis, pomona, icterohaemorrhagiae, and seramanga in Primata (Cebidae). Prevalence was positively correlated with humidity and temperature, with significantly higher prevalence at the site characterized by high humidity, severe flooding because of rainfall, and warm weather throughout the year. All positive animals were classified as clinically asymptomatic, meaning that antibodies from a current or past infection were detected but no overt symptoms were apparent. The diversity of serovars observed and the taxon-specific nature of these associations suggest that the epidemiology of Leptospira transmission is likely to be complex and multidimensional. The strong association observed between prevalence and climate suggests that the important role of climate as an indicator of Leptospira infection risk in humans may also be applicable to wildlife. Future studies in both wild and captive populations of Neotropical wildlife will further elucidate this disease interplay.
Keyword Conservation biology
Epidemiology
Microagglutination test
Primates
Zoo mammals
Zoonosis
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Veterinary Science Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 4 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 4 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Mon, 08 Feb 2016, 21:49:54 EST by Viviana Gonzalez Astudillo on behalf of School of Veterinary Science