Remineralization of initial enamel carious lesions using fluoridated milk in vitro

Ongtenco, Kristine L., Anthonappa, Robert P., Itthagarun, Anut, King, Nigel M., Lalloo, Ratilal and Nair, Raj G. (2014) Remineralization of initial enamel carious lesions using fluoridated milk in vitro. Acta odontologica Scandinavica, 72 8: 737-744. doi:10.3109/00016357.2014.903515


Author Ongtenco, Kristine L.
Anthonappa, Robert P.
Itthagarun, Anut
King, Nigel M.
Lalloo, Ratilal
Nair, Raj G.
Title Remineralization of initial enamel carious lesions using fluoridated milk in vitro
Formatted title
Remineralization of initial enamel carious lesions using fluoridated milk in vitro
Journal name Acta odontologica Scandinavica   Check publisher's open access policy
ISSN 1502-3850
0001-6357
Publication date 2014-11-01
Year available 2014
Sub-type Article (original research)
DOI 10.3109/00016357.2014.903515
Open Access Status Not yet assessed
Volume 72
Issue 8
Start page 737
End page 744
Total pages 8
Place of publication Abingdon, Oxfordshire, United Kingdom
Publisher Taylor & Francis
Language eng
Formatted abstract
Objectives. Milk is a universal dietary component and it is now recognized as an effective medium for the delivery of fluoride (F). This study sought (i) to evaluate fluoridated milk (2.5 ppm, 5 ppm, 10 ppm) for remineralizing carious lesions and (ii) to determine the optimum frequency for treating carious lesions with fluoridated milk.

Materials and methods. Artificial carious lesions, 90–180 μm deep, were created on extracted third molar teeth that were sectioned to produce specimens of 100–120 μm thickness. Specimens were randomly divided into 13 groups (n = 20) for treatment with deionized water, plain milk or fluoridated milk (2.5 ppm, 5 ppm, 10 ppm); once daily, twice daily or on alternate days as part of a 20-day pH cycling model. Lesion depth (LD) and mineral content were evaluated before and after pH cycling. Paired t-test, ANOVA and Student-Newman-Keuls tests were employed to make comparisons within and between the different groups.

Results. Fluoridated milk significantly reduced LD and increased the mineral content of the lesions compared to plain milk and deionized water (p < 0.05). The greatest reduction in LD was with 2.5 ppm F milk used twice daily (p < 0.05).

Conclusions. Milk with 2.5 ppm F used twice daily demonstrated the greatest remineralization of artificial enamel carious lesions in vitro.
Keyword Caries
Demineralization
Fluoride
Milk
Remineralization
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Dentistry Publications
 
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