Reducing sitting time after stroke: a phase II safety and feasibility randomized controlled trial

English, Coralie, Healy, Genevieve N., Olds, Tim, Parfitt, Gaynor, Borkoles, Erika, Coates, Alison, Kramer, Sharon and Bernhardt, Julie (2016) Reducing sitting time after stroke: a phase II safety and feasibility randomized controlled trial. Archives of Physical Medicine and Rehabilitation, 97 2: 273-280. doi:10.1016/j.apmr.2015.10.094

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Author English, Coralie
Healy, Genevieve N.
Olds, Tim
Parfitt, Gaynor
Borkoles, Erika
Coates, Alison
Kramer, Sharon
Bernhardt, Julie
Title Reducing sitting time after stroke: a phase II safety and feasibility randomized controlled trial
Journal name Archives of Physical Medicine and Rehabilitation   Check publisher's open access policy
ISSN 1532-821X
Publication date 2016-02
Sub-type Article (original research)
DOI 10.1016/j.apmr.2015.10.094
Open Access Status File (Author Post-print)
Volume 97
Issue 2
Start page 273
End page 280
Total pages 8
Place of publication Maryland Heights, MO, United States
Publisher W.B. Saunders
Collection year 2017
Language eng
Formatted abstract
Objective: To test the safety, feasibility, and effectiveness of reducing sitting time in stroke survivors.
Design: Randomized controlled trial with attention-matched controls and blinded assessments.
Setting: Community.
Participants: Stroke survivors (N=35; 22 men; mean age, 66.9±12.7y).
Interventions: Four counseling sessions over 7 weeks with a message of sit less and move more (intervention group) or calcium for bone health (attention-matched control group).
Main Outcome Measures: Measures included safety (adverse events, increases in pain, spasticity, or fatigue) and feasibility (adherence to trial protocol). Secondary measures included time spent sitting (including in prolonged bouts ≥30min), standing, and stepping as measured by the thigh-worn inclinometer (7d, 24h/d protocol) and time spent in physical activity of at least moderate intensity as measured by a triaxial accelerometer. The Multimedia Activity Recall for Children and Adults was used to describe changes in use of time.
Results: Thirty-three participants completed the full protocol. Four participants reported falls during the intervention period with no other adverse events. From a baseline average of 640.7±99.6min/d, daily sitting time reduced on average by 30±50.6min/d (95% confidence interval [CI], 5.8–54.6) in the intervention group and 40.4±92.5min/d in the control group (95% CI, 13.0–93.8). Participants in both groups also reduced their time spent in prolonged sitting bouts (≥30min) and increased time spent standing and stepping.
Conclusions: Our protocol was both safe and feasible. Participants in both groups spent less time sitting and more time standing and stepping postintervention, but outcomes were not superior for intervention participants. Attention matching is desirable in clinical trials and may have contributed to the positive outcomes for control participants.
Keyword Exercise
Sedentary lifestyle
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
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