The match between common antibiotics packaging and guidelines for their use in Australia

McGuire, Treasure M., Smith, Jane and Del Mar, Chris (2015) The match between common antibiotics packaging and guidelines for their use in Australia. Australian and New Zealand Journal of Public Health, 39 6: 569-572. doi:10.1111/1753-6405.12385

Author McGuire, Treasure M.
Smith, Jane
Del Mar, Chris
Title The match between common antibiotics packaging and guidelines for their use in Australia
Journal name Australian and New Zealand Journal of Public Health   Check publisher's open access policy
ISSN 1753-6405
Publication date 2015-12-01
Year available 2015
Sub-type Article (original research)
DOI 10.1111/1753-6405.12385
Open Access Status DOI
Volume 39
Issue 6
Start page 569
End page 572
Total pages 4
Place of publication Richmond, VIC Australia
Publisher Wiley-Blackwell Publishing Asia
Collection year 2016
Language eng
Formatted abstract
Objectives: To determine the potential for a source of surplus antibiotics in the community to come from the mismatch between the recommended duration of antibiotic treatment for common indications in primary care and that dictated by default pharmaceutical industry packaging.

Methods: Analysis of existing published information of: 1) the most common antibiotics prescribed in primary care in Australia; 2) their most common indications; 3) the guideline recommendations for their duration; and 4) the duration dictated by antibiotic packaging.

Results: Of 32 common antibiotic prescribing scenarios, 10 had doses left over in surplus and 18 had a shortfall, leaving only four in which the packaging size matched the duration recommended by electronic Therapeutic Guidelines. Where there was a shortfall, this was only exactly accommodated by a repeat prescription in two cases.

Conclusions: Mismatch contributes to a shortfall or excess of doses compared to recommended antibiotic treatment protocols and probably exaggerates redundant doses in the community from prescribed antibiotics dispensed and not consumed.

Implications: Prescribers need to be aware that the mismatch between antibiotic pack sizes and guideline recommendations for their duration is contributing to antibiotic resistance in the community.
Keyword Infectious diseases
Antibiotic resistance
Drug utilisation
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Pharmacy Publications
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