Neuronal and inducible nitric oxide synthase upregulation in the rat medial prefrontal cortex following acute restraint stress: a dataset

Spiers, Jereme G., Chen, Hsiao-Jou Cortina, Lee, Johnny K., Sernia, Conrad and Lavidis, Nickolas A. (2016) Neuronal and inducible nitric oxide synthase upregulation in the rat medial prefrontal cortex following acute restraint stress: a dataset. Data in Brief, 6 582-586. doi:10.1016/j.dib.2016.01.005


Author Spiers, Jereme G.
Chen, Hsiao-Jou Cortina
Lee, Johnny K.
Sernia, Conrad
Lavidis, Nickolas A.
Title Neuronal and inducible nitric oxide synthase upregulation in the rat medial prefrontal cortex following acute restraint stress: a dataset
Journal name Data in Brief   Check publisher's open access policy
ISSN 2352-3409
Publication date 2016-03
Sub-type Article (original research)
DOI 10.1016/j.dib.2016.01.005
Open Access Status DOI
Volume 6
Start page 582
End page 586
Total pages 5
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Collection year 2017
Subject 1000 General
3304 Education
Formatted abstract
This data article provides additional evidence on gene expression changes in the neuronal and inducible isoforms of nitric oxide synthase in the medial prefrontal cortex following acute stress. Male Wistar rats aged 6-8 weeks were exposed to control or restraint stress conditions for up to four hours in the dark cycle after which the brain was removed and the medial prefrontal cortex isolated by cryodissection. Following RNA extraction and cDNA synthesis, gene expression data were measured using quantitative real-time PCR. The mRNA levels of the neuronal and inducible nitric oxide synthase isoforms, and the inhibitory subunit of NF-κB, I kappa B alpha were determined using the δδCT method relative to control animals. This data article presents complementary results related to the research article entitled 'Acute restraint stress induces specific changes in nitric oxide production and inflammatory markers in the rat hippocampus and striatum' [1].
Keyword Medial prefrontal cortex
Nitric oxide synthase
Stress
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Biomedical Sciences Publications
 
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