Prevalence of malaria across Papua New Guinea after initial roll-out of insecticide-treated mosquito nets

Hetzel, Manuel W., Morris, Hector, Tarongka, Nandao, Barnadas, Celine, Pulford, Justin, Makita, Leo, Siba, Peter M. and Mueller, Ivo (2015) Prevalence of malaria across Papua New Guinea after initial roll-out of insecticide-treated mosquito nets. Tropical Medicine and International Health, 20 12: 1745-1755. doi:10.1111/tmi.12616


Author Hetzel, Manuel W.
Morris, Hector
Tarongka, Nandao
Barnadas, Celine
Pulford, Justin
Makita, Leo
Siba, Peter M.
Mueller, Ivo
Title Prevalence of malaria across Papua New Guinea after initial roll-out of insecticide-treated mosquito nets
Journal name Tropical Medicine and International Health   Check publisher's open access policy
ISSN 1365-3156
1360-2276
Publication date 2015-12
Year available 2015
Sub-type Article (original research)
DOI 10.1111/tmi.12616
Open Access Status DOI
Volume 20
Issue 12
Start page 1745
End page 1755
Total pages 11
Place of publication Chichester, West Sussex, United Kingdom
Publisher Wiley-Blackwell Publishing
Collection year 2016
Language eng
Formatted abstract
Objectives To assess the population prevalence of malaria in villages across Papua New Guinea (PNG) following the first roll-out of free long-lasting insecticidal nets (LLIN).

Methods Between October 2008 and August 2009, a household survey was conducted in 49 random villages in districts covered by the LLIN distribution campaign. The survey extended to 19 villages in sentinel sites that had not yet been covered by the campaign. In each village, 30 households were randomly sampled, household heads were interviewed and capillary blood samples were collected from all consenting household members for microscopic diagnosis of malaria.

Results 
Malaria prevalence ranged from 0% to 49.7% with a weighted average of 12.1% (95% CI 9.5, 15.3) in the national sample. More people were infected with Plasmodium falciparum (7.0%; 95% CI 5.4, 9.1) than with P. vivax (3.8%; 95% CI 2.4, 5.7) or P. malariae (0.3%; 95% CI 0.1, 0.6). Parasitaemia was strongly age-dependent with a P. falciparum peak at age 5–9 years and a P. vivax peak at age 1–4 years, yet with differences between geographical regions. Individual LLIN use and high community coverage were associated with reduced odds of infection (OR = 0.64 and 0.07, respectively; both P < 0.001). Splenomegaly in children and anaemia were common morbidities attributable to malaria.

Conclusions Malaria prevalence across PNG is again at levels comparable to the 1970s. The strong association of LLIN use with reduced parasitaemia supports efforts to achieve and maintain high country-wide coverage. P. vivax infections will require special targeted approaches across PNG.
Keyword Insecticide-treated Bednets
Falciparum malaria
Vivax malaria
Papua New Guinea
Surveys
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Public Health Publications
 
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