Empirical Bayes for group (DCM) studies: a reproducibility study

Litvak, Vladimir, Garrido, Marta, Zeidman, Peter and Friston, Karl (2015) Empirical Bayes for group (DCM) studies: a reproducibility study. Frontiers in Human Neuroscience, 9 DEC: 670.1-670.12. doi:10.3389/fnhum.2015.00670


Author Litvak, Vladimir
Garrido, Marta
Zeidman, Peter
Friston, Karl
Title Empirical Bayes for group (DCM) studies: a reproducibility study
Journal name Frontiers in Human Neuroscience   Check publisher's open access policy
ISSN 1662-5161
Publication date 2015-12-22
Sub-type Article (original research)
DOI 10.3389/fnhum.2015.00670
Open Access Status DOI
Volume 9
Issue DEC
Start page 670.1
End page 670.12
Total pages 12
Place of publication Lausanne, Switzerland
Publisher Frontiers Research Foundation
Collection year 2016
Language eng
Abstract This technical note addresses some key reproducibility issues in the dynamic causal modelling of group studies of event related potentials. Specifically, we address the reproducibility of Bayesian model comparison (and inferences about model parameters) from three important perspectives namely: (i) reproducibility with independent data (obtained by averaging over odd and even trials); (ii) reproducibility over formally distinct models (namely, classic ERP and canonical microcircuit or CMC models); and (iii) reproducibility over inversion schemes (inversion of the grand average and estimation of group effects using empirical Bayes). Our hope was to illustrate the degree of reproducibility one can expect from DCM when analysing different data, under different models with different analyses.
Keyword Empirical Bayes
Random effects
Fixed effects
Dynamic causal modelling
Bayesian model reduction
Reproducibility
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Queensland Brain Institute Publications
Official 2016 Collection
Centre for Advanced Imaging Publications
 
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