The Global Burden of Cancer 2013

Fitzmaurice, Christina, Dicker, Daniel, Pain, Amanda, Hamavid, Hannah, Moradi-Lakeh, Maziar, MacIntyre, Michael F., Allen, Christine, Hansen, Gillian, Woodbrook, Rachel, Wolfe, Charles, Hamadeh, Randah R., Moore, Ami, Werdecker, Andrea, Gessner, Bradford D., Te Ao, Braden, McMahon, Brian, Karimkhani, Chante, Yu, Chuanhua, Cooke, Graham S., Schwebel, David C., Carpenter, David O., Pereira, David M., Nash, Denis, Kazi, Dhruv S., De Leo, Diego, Plass, Dietrich, Ukwaja, Kingsley N., Thurston, George D., Yun Jin, Kim, Simard, Edgar P., Mills, Edward, Park, Eun-Kee, Catala-Lopez, Ferran, deVeber, Gabrielle, Gotay, Carolyn, Khan, Gulfaraz, Hosgood, H. Dean 3rd, Santos, Itamar S., Leasher, Janet L., Singh, Jasvinder, Leigh, James, Jonas, Jost, Sanabria, Juan, Beardsley, Justin, Jacobsen, Kathryn H., Takahashi, Ken, Franklin, Richard C., Ronfani, Luca, Montico, Marcella, Naldi, Luigi, Tonelli, Marcello, Geleijnse, Johanna, Petzold, Max, Shrime, Mark G., Younis, Mustafa, Yonemoto, Naohiro, Breitborde, Nicholas, Yip, Paul, Pourmalek, Farshad, Lotufo, Paulo A., Esteghamati, Alireza, Hankey, Graeme J., Ali, Raghib, Lunevicius, Raimundas, Malekzadeh, Reza, Dellavalle, Robert, Weintraub, Robert, Lucas, Robyn, Hay, Roderick, Rojas-Rueda, David, Westerman, Ronny, Sepanlou, Sadaf G., Nolte, Sandra, Patten, Scott, Weichenthal, Scott, Abera, Semaw Ferede, Fereshtehnejad, Seyed-Mohammad, Shiue, Ivy, Driscoll, Tim, Vasankari, Tommi, Alsharif, Ubai, Rahimi-Movaghar, Vafa, Vlassov, Vasiliy V., Marcenes, W. S., Mekonnen, Wubegzier, Melaku, Yohannes Adama, Yano, Yuichiro, Artaman, Al, Campos, Ismael, MacLachlan, Jennifer, Mueller, Ulrich, Kim, Daniel, Trillini, Matias, Eshrati, Babak, Williams, Hywel C., Shibuya, Kenji, Dandona, Rakhi, Murthy, Kinnari, Cowie, Benjamin, Amare, Azmeraw T., Antonio, Carl Abelardo, Castaneda-Orjuela, Carlos, van Gool, Coen H., Violante, Francesco, Oh, In-Hwan, Deribe, Kedede, Soreide, Kjetil, Knibbs, Luke, Kereselidze, Maia, Green, Mark, Cardenas, Rosario, Roy, Nobhojit, Tillman, Taavi, Li, Yongmei, Krueger, Hans, Monasta, Lorenzo, Dey, Subhojit, Sheikhbahaei, Sara, Hafezi-Nejad, Nima, Kumar, G. Anil, Chandrashekhar T., Dandona, Lalit, Wang, Haidong, Vollset, Stein Emil, Mokdad, Ali, Salomon, Joshua A., Lozano, Rafael, Vos, Theo, Forouzanfar, Mohammad, Lopez, Alan, Murray, Christopher, Naghavi, Mohsen and Global Burden of Disease Cancer Collaboration (2015) The Global Burden of Cancer 2013. JAMA Oncology, 1 4: 505-527. doi:10.1001/jamaoncol.2015.0735


Author Fitzmaurice, Christina
Dicker, Daniel
Pain, Amanda
Hamavid, Hannah
Moradi-Lakeh, Maziar
MacIntyre, Michael F.
Allen, Christine
Hansen, Gillian
Woodbrook, Rachel
Wolfe, Charles
Hamadeh, Randah R.
Moore, Ami
Werdecker, Andrea
Gessner, Bradford D.
Te Ao, Braden
McMahon, Brian
Karimkhani, Chante
Yu, Chuanhua
Cooke, Graham S.
Schwebel, David C.
Carpenter, David O.
Pereira, David M.
Nash, Denis
Kazi, Dhruv S.
De Leo, Diego
Plass, Dietrich
Ukwaja, Kingsley N.
Thurston, George D.
Yun Jin, Kim
Simard, Edgar P.
Mills, Edward
Park, Eun-Kee
Catala-Lopez, Ferran
deVeber, Gabrielle
Gotay, Carolyn
Khan, Gulfaraz
Hosgood, H. Dean 3rd
Santos, Itamar S.
Leasher, Janet L.
Singh, Jasvinder
Leigh, James
Jonas, Jost
Sanabria, Juan
Beardsley, Justin
Jacobsen, Kathryn H.
Takahashi, Ken
Franklin, Richard C.
Ronfani, Luca
Montico, Marcella
Naldi, Luigi
Tonelli, Marcello
Geleijnse, Johanna
Petzold, Max
Shrime, Mark G.
Younis, Mustafa
Yonemoto, Naohiro
Breitborde, Nicholas
Yip, Paul
Pourmalek, Farshad
Lotufo, Paulo A.
Esteghamati, Alireza
Hankey, Graeme J.
Ali, Raghib
Lunevicius, Raimundas
Malekzadeh, Reza
Dellavalle, Robert
Weintraub, Robert
Lucas, Robyn
Hay, Roderick
Rojas-Rueda, David
Westerman, Ronny
Sepanlou, Sadaf G.
Nolte, Sandra
Patten, Scott
Weichenthal, Scott
Abera, Semaw Ferede
Fereshtehnejad, Seyed-Mohammad
Shiue, Ivy
Driscoll, Tim
Vasankari, Tommi
Alsharif, Ubai
Rahimi-Movaghar, Vafa
Vlassov, Vasiliy V.
Marcenes, W. S.
Mekonnen, Wubegzier
Melaku, Yohannes Adama
Yano, Yuichiro
Artaman, Al
Campos, Ismael
MacLachlan, Jennifer
Mueller, Ulrich
Kim, Daniel
Trillini, Matias
Eshrati, Babak
Williams, Hywel C.
Shibuya, Kenji
Dandona, Rakhi
Murthy, Kinnari
Cowie, Benjamin
Amare, Azmeraw T.
Antonio, Carl Abelardo
Castaneda-Orjuela, Carlos
van Gool, Coen H.
Violante, Francesco
Oh, In-Hwan
Deribe, Kedede
Soreide, Kjetil
Knibbs, Luke
Kereselidze, Maia
Green, Mark
Cardenas, Rosario
Roy, Nobhojit
Tillman, Taavi
Li, Yongmei
Krueger, Hans
Monasta, Lorenzo
Dey, Subhojit
Sheikhbahaei, Sara
Hafezi-Nejad, Nima
Kumar, G. Anil
Chandrashekhar T.
Dandona, Lalit
Wang, Haidong
Vollset, Stein Emil
Mokdad, Ali
Salomon, Joshua A.
Lozano, Rafael
Vos, Theo
Forouzanfar, Mohammad
Lopez, Alan
Murray, Christopher
Naghavi, Mohsen
Global Burden of Disease Cancer Collaboration
Title The Global Burden of Cancer 2013
Journal name JAMA Oncology   Check publisher's open access policy
ISSN 2374-2445
2374-2437
Publication date 2015-07
Sub-type Article (original research)
DOI 10.1001/jamaoncol.2015.0735
Open Access Status DOI
Volume 1
Issue 4
Start page 505
End page 527
Total pages 23
Place of publication Chicago, United States
Publisher American Medical Association
Collection year 2016
Language eng
Formatted abstract
Importance Cancer:  is among the leading causes of death worldwide. Current estimates of cancer burden in individual countries and regions are necessary to inform local cancer control strategies.

Objective:   To estimate mortality, incidence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs) for 28 cancers in 188 countries by sex from 1990 to 2013.

Evidence Review:   The general methodology of the Global Burden of Disease (GBD) 2013 study was used. Cancer registries were the source for cancer incidence data as well as mortality incidence (MI) ratios. Sources for cause of death data include vital registration system data, verbal autopsy studies, and other sources. The MI ratios were used to transform incidence data to mortality estimates and cause of death estimates to incidence estimates. Cancer prevalence was estimated using MI ratios as surrogates for survival data; YLDs were calculated by multiplying prevalence estimates with disability weights, which were derived from population-based surveys; YLLs were computed by multiplying the number of estimated cancer deaths at each age with a reference life expectancy; and DALYs were calculated as the sum of YLDs and YLLs.

Findings:   In 2013 there were 14.9 million incident cancer cases, 8.2 million deaths, and 196.3 million DALYs. Prostate cancer was the leading cause for cancer incidence (1.4 million) for men and breast cancer for women (1.8 million). Tracheal, bronchus, and lung (TBL) cancer was the leading cause for cancer death in men and women, with 1.6 million deaths. For men, TBL cancer was the leading cause of DALYs (24.9 million). For women, breast cancer was the leading cause of DALYs (13.1 million). Age-standardized incidence rates (ASIRs) per 100 000 and age-standardized death rates (ASDRs) per 100 000 for both sexes in 2013 were higher in developing vs developed countries for stomach cancer (ASIR, 17 vs 14; ASDR, 15 vs 11), liver cancer (ASIR, 15 vs 7; ASDR, 16 vs 7), esophageal cancer (ASIR, 9 vs 4; ASDR, 9 vs 4), cervical cancer (ASIR, 8 vs 5; ASDR, 4 vs 2), lip and oral cavity cancer (ASIR, 7 vs 6; ASDR, 2 vs 2), and nasopharyngeal cancer (ASIR, 1.5 vs 0.4; ASDR, 1.2 vs 0.3). Between 1990 and 2013, ASIRs for all cancers combined (except nonmelanoma skin cancer and Kaposi sarcoma) increased by more than 10% in 113 countries and decreased by more than 10% in 12 of 188 countries.

Conclusions and Relevance:
  Cancer poses a major threat to public health worldwide, and incidence rates have increased in most countries since 1990. The trend is a particular threat to developing nations with health systems that are ill-equipped to deal with complex and expensive cancer treatments. The annual update on the Global Burden of Cancer will provide all stakeholders with timely estimates to guide policy efforts in cancer prevention, screening, treatment, and palliation.
Q-Index Code CX
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Public Health Publications
 
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Created: Fri, 08 Jan 2016, 14:26:10 EST by Luke Knibbs on behalf of School of Public Health