Muscle growth is reduced in 15-month-old children with cerebral palsy

Herskind, Anna, Ritterband-Rosenbaum, Anina, Willerslev-Olsen, Maria, Lorentzen, Jakob, Hanson, Lars, Lichtwark, Glen and Nielsen, Jens B. (2015) Muscle growth is reduced in 15-month-old children with cerebral palsy. Developmental Medicine and Child Neurology, 58 5: 485-491. doi:10.1111/dmcn.12950

Author Herskind, Anna
Ritterband-Rosenbaum, Anina
Willerslev-Olsen, Maria
Lorentzen, Jakob
Hanson, Lars
Lichtwark, Glen
Nielsen, Jens B.
Title Muscle growth is reduced in 15-month-old children with cerebral palsy
Journal name Developmental Medicine and Child Neurology   Check publisher's open access policy
ISSN 1469-8749
Publication date 2015
Year available 2015
Sub-type Article (original research)
DOI 10.1111/dmcn.12950
Open Access Status Not Open Access
Volume 58
Issue 5
Start page 485
End page 491
Total pages 7
Place of publication Chichester, West Sussex United Kingdom
Publisher Wiley-Blackwell Publishing
Collection year 2016
Language eng
Formatted abstract
Lack of muscle growth relative to bone growth may be responsible for development of contractures in children with cerebral palsy (CP). Here, we used ultrasonography to compare growth of the medial gastrocnemius muscle in children with and without CP.

Twenty-six children with spastic CP (15 males, 11 females; mean age 35mo, range 8–65mo) and 101 typically developing children (47 males, 54 females; mean age 29mo, range 1–69mo) were included. Functional abilities of children with CP equalled levels I to III in the Gross Motor Function Classification System. Medial gastrocnemius muscle volume was constructed from serial, transverse, two-dimensional ultrasonography images.

In typically developing children, medial gastrocnemius volume increased linearly with age. Among children with CP, medial gastrocnemius volume increased less with age and deviated significantly from typically developing children at 15 months of age (p<0.05). Bone length increased with age without significant difference (p=0.49).

Muscle growth in children with CP initially follows that of typically developing children, but decreases at 15 months of age. This may be related to reduced physical activity and neural activation of the muscle. Interventions stimulating muscle growth in young children with CP may be important to prevent contractures.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Human Movement and Nutrition Sciences Publications
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Created: Thu, 07 Jan 2016, 15:00:14 EST by Sandrine Ducrot on behalf of School of Human Movement and Nutrition Sciences