Quantitating aortic regurgitation by cardiovascular magnetic resonance: significant variations due to slice location and breath holding

Chaturvedi, Abhishek, Hamilton-Craig, Christian, Cawley, Peter J., Mitsumori, Lee M., Otto, Catherine M. and Maki, Jeffrey H. (2015) Quantitating aortic regurgitation by cardiovascular magnetic resonance: significant variations due to slice location and breath holding. European Radiology, 1-10. doi:10.1007/s00330-015-4120-6


Author Chaturvedi, Abhishek
Hamilton-Craig, Christian
Cawley, Peter J.
Mitsumori, Lee M.
Otto, Catherine M.
Maki, Jeffrey H.
Title Quantitating aortic regurgitation by cardiovascular magnetic resonance: significant variations due to slice location and breath holding
Journal name European Radiology   Check publisher's open access policy
ISSN 1432-1084
0938-7994
Publication date 2015-12-03
Year available 2015
Sub-type Article (original research)
DOI 10.1007/s00330-015-4120-6
Open Access Status Not yet assessed
Start page 1
End page 10
Total pages 10
Place of publication Heidelberg, Germany
Publisher Springer
Collection year 2016
Language eng
Formatted abstract
Objectives Compare variability in flow measurements by phase contrast MRI, performed at different locations in the aorta and pulmonary artery (PA) using breath-held (BH) and free-breathing (FB) sequences.

Methods Fifty-seven patients with valvular heart disease, confirmed by echocardiography, were scanned using BH technique at 3 locations in the ascending aorta (SOV = sinus of Valsalva, STJ = sinotubular junction, ASC = ascending aorta at level of right pulmonary artery) and 2 locations in PA. Single FB measurement was obtained at STJ for aorta. Obtained metrics (SV = stroke volume, FV = forward volume, BV = backward volume, RF = regurgitant fraction) were evaluated separately for patients with aortic regurgitation (AR, n = 31) and mitral regurgitation (n = 26).

Results No difference was noted between the two measurements in the PA. Significant differences were noted in measured SV at different aortic locations. SV measurements obtained at ASC correlated best with the measurements obtained in the PA. Strongest correlation of AR was measured at the STJ.

Conclusion Measurements of flow volumes by phase contrast MRI differ depending on slice location. When using stroke volumes to calculate pulmonary to systemic blood flow ratio (Qp/Qs), ASC should be used. For quantifying aortic regurgitation, measurement should be obtained at STJ.

Key Points
• Aortic regurgitation can be accurately measured by MRI.
• Aortic regurgitation measurement by MRI varies according to the location where measured.
• Aortic regurgitation can also be measured by MRI without breath hold.
Keyword Magnetic resonance imaging
Phase contrast
Aortic regurgitation
Quantification
Free breathing
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Medicine Publications
Centre for Advanced Imaging Publications
 
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