A large and diverse collection of bovine genome sequences from the Canadian Cattle Genome Project

Stothard, Paul, Liao, Xiaoping, Arantes, Adriano S., De Pauw, Mary, Coros, Colin, Plastow, Graham S., Sargolzaei, Mehdi, Crowley, John J., Basarab, John A., Schenkel, Flavio, Moore, Stephen and Miller, Stephen P. (2015) A large and diverse collection of bovine genome sequences from the Canadian Cattle Genome Project. Gigascience, 4 49: . doi:10.1186/s13742-015-0090-5


Author Stothard, Paul
Liao, Xiaoping
Arantes, Adriano S.
De Pauw, Mary
Coros, Colin
Plastow, Graham S.
Sargolzaei, Mehdi
Crowley, John J.
Basarab, John A.
Schenkel, Flavio
Moore, Stephen
Miller, Stephen P.
Title A large and diverse collection of bovine genome sequences from the Canadian Cattle Genome Project
Journal name Gigascience   Check publisher's open access policy
ISSN 2047-217X
Publication date 2015-10-26
Sub-type Article (original research)
DOI 10.1186/s13742-015-0090-5
Open Access Status DOI
Volume 4
Issue 49
Total pages 3
Place of publication London, United Kingdom
Publisher BioMed Central
Collection year 2016
Language eng
Formatted abstract
Background: The Canadian Cattle Genome Project is a large-scale international project that aims to develop genomics-based tools to enhance the efficiency and sustainability of beef and dairy production. Obtaining DNA sequence information is an important part of achieving this goal as it facilitates efforts to associate specific DNA differences with phenotypic variation. These associations can be used to guide breeding decisions and provide valuable insight into the molecular basis of traits.

Findings:  We describe a dataset of 379 whole-genome sequences, taken primarily from key historic Bos taurus animals, along with the analyses that were performed to assess data quality. The sequenced animals represent ten populations relevant to beef or dairy production. Animal information (name, breed, population), sequence data metrics (mapping rate, depth, concordance), and sequence repository identifiers (NCBI BioProject and BioSample IDs) are provided to enable others to access and exploit this sequence information.

Conclusions:  The large number of whole-genome sequences generated as a result of this project will contribute to ongoing work aiming to catalogue the variation that exists in cattle as well as efforts to improve traits through genotype-guided selection. Studies of gene function, population structure, and sequence evolution are also likely to benefit from the availability of this resource.
Keyword Whole-genome sequencing
Bos taurus
Beef
Dairy
Q-Index Code CX
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
Queensland Alliance for Agriculture and Food Innovation
QAAFI Biological Information Technology (QBIT) Publications
 
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