Determining the microbiological cause of a chest infection

Clark, Julia E. (2015) Determining the microbiological cause of a chest infection. Archives of Disease in Childhood, 100 2: 193-197. doi:10.1136/archdischild-2013-305742

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Author Clark, Julia E.
Title Determining the microbiological cause of a chest infection
Journal name Archives of Disease in Childhood   Check publisher's open access policy
ISSN 1468-2044
0003-9888
Publication date 2015-02-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1136/archdischild-2013-305742
Open Access Status Not Open Access
Volume 100
Issue 2
Start page 193
End page 197
Total pages 5
Place of publication London, United Kingdom
Publisher B M J Group
Collection year 2016
Language eng
Abstract Over recent years non-culture techniques such as specific viral and bacterial nucleic acid amplification, serology and antigen detection have considerably developed and been applied within research studies to clinical samples, significantly increasing pathogen detection in pneumonia. There are promising signs of improved diagnostic yields for pneumococcal pneumonia when using molecular techniques to detect pneumococcal gene sequences in blood or by combining serum biomarkers with rapid pneumococcal urinary antigen testing. Pathogens have traditionally been difficult to detect in pneumonia and treatment is usually successful with empiric antibiotics. However, directed antibiotic treatment has significant benefits in terms of antibiotic stewardship and these new technologies make this goal a possibility, though not yet a reality.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2016 Collection
School of Medicine Publications
 
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