Changing status of investigations for prostate cancer detection

Gordon, Lachlan A. N., Yaxley, John, Frydenberg, Mark, Williams, Scott G and Gardiner, Robert A. (2015) Changing status of investigations for prostate cancer detection. Cancer Forum, 39 3: 164-168.

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Name Description MIMEType Size Downloads
Author Gordon, Lachlan A. N.
Yaxley, John
Frydenberg, Mark
Williams, Scott G
Gardiner, Robert A.
Title Changing status of investigations for prostate cancer detection
Journal name Cancer Forum   Check publisher's open access policy
ISSN 0311-306X
Publication date 2015
Sub-type Article (original research)
Open Access Status Not Open Access
Volume 39
Issue 3
Start page 164
End page 168
Total pages 5
Place of publication Sydney, NSW, Australia
Publisher Cancer Council Australia
Collection year 2016
Language eng
Abstract Before the introduction of serum prostate specific antigen for the early detection of prostate cancer, this condition was diagnosed at an advanced stage, with palliative androgen deprivation therapy the mainstay of management. Increasing use of prostate specific antigen testing has resulted in a significant stage shift from locally advanced/metastatic disease to early stage, lower volume prostate cancer. Prostate specific antigen testing provides the potential for life-threatening disease to be detected early enough for effective treatment. However, many asymptomatic men with low-risk prostate cancer have also had what were, in retrospect, unnecessary diagnostic procedures and treatments leading to management-related morbidity. This manuscript traces the changes that have occurred and are occurring to refine detection, with the integration of new technologies to uncouple diagnosis from management so that potentially curative treatment can be tailored to those who are most likely to benefit.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: UQ Centre for Clinical Research Publications
Official 2016 Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 2 times in Thomson Reuters Web of Science Article | Citations
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Created: Fri, 11 Dec 2015, 15:28:11 EST by Frank Gardiner on behalf of Surgery - Royal Brisbane and Women's Hospital