Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Systematic Review and Australian Case Series Examining Cognitive Outcomes

Gemma Mckeon (2015). Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Systematic Review and Australian Case Series Examining Cognitive Outcomes Professional Doctorate, School of Psychology, The University of Queensland.

       
Attached Files (Some files may be inaccessible until you login with your UQ eSpace credentials)
Name Description MIMEType Size Downloads
s4138809_pd_abstract.pdf s4138809_pd_abstract.pdf application/pdf 88.35KB 0
s4138809_pd_totalthesis.pdf s4138809_pd_totalthesis.pdf application/pdf 2.69MB 0
Author Gemma Mckeon
Thesis Title Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Systematic Review and Australian Case Series Examining Cognitive Outcomes
School, Centre or Institute School of Psychology
Institution The University of Queensland
Publication date 2015-12-09
Thesis type Professional Doctorate
Supervisor Dr Gail Robinson
Dr Donna Spooner
Total pages 278
Total colour pages 3
Total black and white pages 275
Language eng
Subjects 17 Psychology and Cognitive Sciences
170101 Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)
Abstract/Summary Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a recently characterised neurological disorder associated with antibodies to the NMDAR. Patterns and predictors of cognitive performance following treatment for this potentially fatal disease have not been extensively researched. Cognitive dysfunction and associated adverse functional implications is, however, potentially a major problem for many patients from this population. This dissertation seeks to address this significant literature shortcoming through two separate but related studies. The first is a systematic review of the published literature reporting cognitive outcomes in anti-NMDAR encephalitis patients following treatment. The second study is a detailed case series of seven anti- NMDAR encephalitis patients. This study sought to address several inadequately researched but important areas of uncertainty identified by the systematic review with respect to the nature and severity of cognitive deficits associated with anti-NMDAR encephalitis. Patterns of neuropsychological functioning are described for each individual patient, and the overall sample. Analyses also examine predictors of cognitive outcomes.
Keyword Encephalitis
Social cognition
Neuropsychological Consequences
autoimmune disease

 
Citation counts: Google Scholar Search Google Scholar
Created: Wed, 09 Dec 2015, 20:20:10 EST by Gemma Mckeon on behalf of Faculty of Health and Behavioural Sciences