Plasma selenium status in a group of Australian blood donors and fresh blood components

McDonald, Charles, Colebourne, Kathryn, Faddy, Helen M., Flower, Robert and Fraser, John F. (2013) Plasma selenium status in a group of Australian blood donors and fresh blood components. Journal of Trace Elements in Medicine and Biology, 27 4: 352-354. doi:10.1016/j.jtemb.2013.06.001


Author McDonald, Charles
Colebourne, Kathryn
Faddy, Helen M.
Flower, Robert
Fraser, John F.
Title Plasma selenium status in a group of Australian blood donors and fresh blood components
Journal name Journal of Trace Elements in Medicine and Biology   Check publisher's open access policy
ISSN 0946-672X
1878-3252
Publication date 2013-10
Year available 2013
Sub-type Letter to editor, brief commentary or brief communication
DOI 10.1016/j.jtemb.2013.06.001
Open Access Status Not yet assessed
Volume 27
Issue 4
Start page 352
End page 354
Total pages 3
Place of publication Muenchen, Germany
Publisher Elsevier GmbH - Urban und Fischer
Language eng
Abstract The purpose of this study was to assess plasma selenium levels in an Australian blood donor population and measure extra-cellular selenium levels in fresh manufactured blood components. Selenium levels were measured using graphite furnace atomic absorption spectrometry with Zeeman background correction. The mean plasma selenium level in healthy plasmapharesis donors was 85.6. ±. 0.5. μg/L and a regional difference was observed between donors in South East Queensland and Far North Queensland. Although participants had selenium levels within the normal range (55.3-110.5. μg/L), 88.5% had levels below 100. μg/L, a level that has been associated with sub-optimal activity of the antioxidant enzyme glutathione peroxidase (GPx). Extra-cellular selenium levels in clinical fresh frozen plasma (cFFP) and apheresis-derived platelets (APH Plt) were within the normal range. Packed red blood cells (PRBC) and pooled buffy coat-derived platelets (BC Plt) had levels at the lower limit of detection, which may have clinical implications to the massively transfused patient.
Keyword Blood donors
Plasmapharesis
Selenium
Transfusion
Q-Index Code CX
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Letter to editor, brief commentary or brief communication
Collection: School of Medicine Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 3 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 4 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Fri, 04 Dec 2015, 19:05:58 EST by System User on behalf of Learning and Research Services (UQ Library)