Cancer vaccines in phase II/III clinical trials: state of the art and future perspectives

Cecco, S., Muraro, E., Giacomin, E., Martorelli, D., Lazzarini, R., Baldo, P. and Dolcetti, R. (2011) Cancer vaccines in phase II/III clinical trials: state of the art and future perspectives. Current Cancer Drug Targets, 11 1: 85-102. doi:10.2174/156800911793743664


Author Cecco, S.
Muraro, E.
Giacomin, E.
Martorelli, D.
Lazzarini, R.
Baldo, P.
Dolcetti, R.
Title Cancer vaccines in phase II/III clinical trials: state of the art and future perspectives
Journal name Current Cancer Drug Targets   Check publisher's open access policy
ISSN 1568-0096
1873-5576
Publication date 2011
Sub-type Article (original research)
DOI 10.2174/156800911793743664
Open Access Status Not yet assessed
Volume 11
Issue 1
Start page 85
End page 102
Total pages 18
Place of publication Bussum, Netherlands
Publisher Bentham Science Publishers
Language eng
Abstract The topic of this review covers a very important branch of cancer research, cancer vaccination. The growing knowledge in tumor immunology has evolved rapidly, starting from unspecific generic stimulation of the immune system to more specific approaches based on the availability of tumor antigens. The review covers molecular and cell biology, and pharmaceutical technology of cancer vaccines. Particularly, it is aimed at highlighting the results of cancer vaccines from phase II and III clinical trials, an issue that is of relevance to better understand how cancer vaccines can successfully complement antitumor therapy, including conventional chemotherapy and the recently developed target-based drugs.
Keyword Cancer
Clinical trials
Immunotherapy
Investigational drugs
Therapeutic vaccines
Tumor-associated antigen
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: UQ Diamantina Institute Publications
 
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