Design and synthesis of periodic mesoporous organosilica materials with a multi-compartment structure

Lin, Chun Xiang Cynthia, Jambhrunkar, Siddharth, Yuan, Pei, Zhou, Chun Hui Clayton and Zhao, George Xiu Song (2015) Design and synthesis of periodic mesoporous organosilica materials with a multi-compartment structure. RSC Advances, 5 109: 89397-89406. doi:10.1039/c5ra16497d


Author Lin, Chun Xiang Cynthia
Jambhrunkar, Siddharth
Yuan, Pei
Zhou, Chun Hui Clayton
Zhao, George Xiu Song
Title Design and synthesis of periodic mesoporous organosilica materials with a multi-compartment structure
Journal name RSC Advances   Check publisher's open access policy
ISSN 2046-2069
Publication date 2015-10-06
Year available 2015
Sub-type Article (original research)
DOI 10.1039/c5ra16497d
Open Access Status Not yet assessed
Volume 5
Issue 109
Start page 89397
End page 89406
Total pages 10
Place of publication Cambridge, United Kingdom
Publisher Royal Society of Chemistry
Collection year 2016
Language eng
Abstract Recently many scientists are interested in replicating the unique structure and function of multi-compartments found in natural cells. Despite the success in recreating multi-compartment structures for organic materials, it is a great challenge to translate a similar concept into inorganic and hybrid materials for more versatile applications. Here, as the first example in the organosilica family, we present a facile synthesis route to create hybrid materials with a multi-compartment structure through the spontaneous assembly of fluorocarbon (FC) and hydrocarbon (HC) surfactants with the addition of co-solvent. The formation of multi-compartment periodic mesoporous organosilica (MCPMO) is triggered by the presence of organic co-solvent that induces an osmotic pressure difference in the system. The MCPMO demonstrates a high loading capacity of the antimalarial and anticancer drug artemisinin (47%) with a sustainable release profile attributed to the unique compartmentalized structure and hydrophobic properties. This synthesis strategy can be extended to design various materials with different compositions and morphologies for wider applications including microelectronics, biomedicine, catalysis and energy storage.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

 
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