Gaining insight into cell wall cellulose macrofibril organisation by simulating microfibril adsorption

Oehme, Daniel P., Doblin, Monika S., Wagner, John, Bacic, Antony, Downton, Matthew T. and Gidley, Michael J. (2015) Gaining insight into cell wall cellulose macrofibril organisation by simulating microfibril adsorption. Cellulose, 22 6: 3501-3520. doi:10.1007/s10570-015-0778-9

Author Oehme, Daniel P.
Doblin, Monika S.
Wagner, John
Bacic, Antony
Downton, Matthew T.
Gidley, Michael J.
Title Gaining insight into cell wall cellulose macrofibril organisation by simulating microfibril adsorption
Journal name Cellulose   Check publisher's open access policy
ISSN 1572-882X
Publication date 2015-12-01
Sub-type Article (original research)
DOI 10.1007/s10570-015-0778-9
Open Access Status Not Open Access
Volume 22
Issue 6
Start page 3501
End page 3520
Total pages 20
Place of publication Dordrecht, Netherlands
Publisher Springer Netherlands
Collection year 2016
Language eng
Abstract One of the most important interactions within the paracrystalline matrix of the plant cell wall occurs between cellulose microfibrils to allow for the formation of larger diameter macrofibrils. Here, we have used computational techniques to investigate how different microfibril surfaces might adsorb onto one another. Molecular dynamics simulations show that limited direct adsorption occurs between non-polar surfaces and free energy of desorption calculations suggest this is due to a high energy barrier for the removal of a single layer of water between these surfaces. Further, it is predicted that when microfibril aggregation occurs, significant conformational changes take place at the surfaces of interaction involving O2 dihedral angles, exocyclic C6 conformation, and microfibril chain tilt. It is more likely that direct interactions initially take place between polar (110) surfaces, and that surface interactions occur between the same types of surface, such as 110 to 110, 1–10 to 1–10 or 200 to 100, where hydrogen bonds can be formed, to stabilise the aggregate. Additionally, we have identified that for the exocyclic group of a glucose residue to change conformation in origin layers, the O2 dihedral in residues before and adjacent to the glucose must rotate to a more cis-like conformation, compared to the trans-like conformation observed in crystalline cellulose. This change in exocyclic conformation occurs due to a slight shift in adjacent chains that preferentially stabilises the exocyclic conformation change in a specific glucose residue of each cellobiose repeat.
Keyword Adsorption
Molecular dynamics
Umbrella sampling
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
Centre for Nutrition and Food Sciences Publications
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Citation counts: TR Web of Science Citation Count  Cited 2 times in Thomson Reuters Web of Science Article | Citations
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