Understanding the occurrence of geriatric syndromes in older surgical patients

McRae, Prudence (2015). Understanding the occurrence of geriatric syndromes in older surgical patients MPhil Thesis, School of Medicine, The University of Queensland. doi:10.14264/uql.2015.1072

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Author McRae, Prudence
Thesis Title Understanding the occurrence of geriatric syndromes in older surgical patients
School, Centre or Institute School of Medicine
Institution The University of Queensland
DOI 10.14264/uql.2015.1072
Publication date 2015-11-20
Thesis type MPhil Thesis
Supervisor Alison Mudge
Nancye Peel
Philip Walker
Total pages 137
Language eng
Subjects 1103 Clinical Sciences
Formatted abstract
The population is ageing and surgery is becoming more common as the treatment of choice for many diseases and conditions in older people. Although mortality rates are low for many operations, older patients are at increased risk of complications and may have poor outcomes including longer hospital stays and discharge to sub-acute care or aged care facilities.

The aim of this thesis was to describe the occurrence of non-disease specific complications, known as geriatric syndromes, in older patients admitted to surgical wards, and to explore the association of ‘frailty’ and other key risk factors with geriatric syndromes and discharge outcomes in order to identify high risk groups who might benefit from interventions designed to prevent these complications and improve discharge outcomes.

The specific aims were to:

1. Describe the occurrence of geriatric syndromes in older surgical ward patients (with the exception of hip fracture or cardiothoracic patients)
2. Investigate the association between key risk factors for geriatric syndromes and discharge outcomes (acute length of stay and discharge destination) in older surgical ward patients.

A literature review of the occurrence of geriatric syndromes in the broader surgical population cared for in usual care wards is presented in Chapter 2(1).

The occurrence of geriatric syndromes in older patients admitted under two surgical subspecialty units is presented in Chapter 3 (2). In this retrospective cohort study of 112 patients aged 65, admitted under the urology or vascular surgical units of Royal Brisbane and Women’s Hospital for three days or more, we found that geriatric syndromes occurred in 32 % of patients. We examined the association of pre-existing impairment in activities of daily living (a unidimensional marker of frailty), mode of admission (elective versus non-elective), extent of surgery (non-operative, minor, major) and surgical sub-specialty unit with ≥1 geriatric syndromes. In multivariable analysis, non-elective admission, major surgery and pre-existing impairment in activities of daily living increased the likelihood of geriatric syndromes. No significant association was seen in the adjusted model with surgical unit, age or comorbidity score.

In Chapter 4, we describe the prevalence of frailty and the occurrence of geriatric syndromes in older vascular surgical ward patients and more precisely examine the association of pre-existing patient factors (frailty and comorbidities), illness severity, surgical severity and mode of admission with ≥1 geriatric syndromes, acute length of stay and discharge destination from the vascular surgical unit. In a prospective cohort study of 110 patients admitted to the vascular surgical unit of Royal Brisbane and Women’s Hospital for three days or more, we found that 39% of participants were frail and 36% developed ≥1 geriatric syndromes. In multivariable analysis, this study found multiple risk factors for geriatric syndromes; frailty and non-elective admission were important predictors for both geriatric syndromes and discharge destination; diabetes with end organ damage was an important predictor of longer length of stay and discharge destination.

In conclusion, these studies add to the evidence that geriatric syndromes are common complications in older surgical ward patients. They contribute to the design of future studies by identifying that frail and non-elective patients are at increased risk and should be the target for interventions to prevent geriatric syndromes and therefore improve outcomes; and identify multiple risk factors for geriatric syndromes and discharge outcomes to be considered when designing or evaluating interventions. Finally, these studies have informed the design of a before-and-after study of an enhanced interdisciplinary model to prevent geriatric syndromes and improve outcomes of vascular surgical elders at Royal Brisbane and Women’s Hospital.

References
1. McRae P, Mudge A, Peel NM, Walker P. Geriatric Syndromes in Older Surgical Patients - A Literature Review. J Frailty Aging. 2013;2(4):205-10.
2. McRae PJ, Peel NM, Walker PJ, de Looze JW, Mudge AM. Geriatric Syndromes in Individuals Admitted to Vascular and Urology Surgical Units. J Am Geriatr Soc. 2014;62 (6):1105-9.
Keyword Geriatric syndromes
Geriatric surgery
Frailty
Predictor
Risk factor

Document type: Thesis
Collections: UQ Theses (RHD) - Official
UQ Theses (RHD) - Open Access
 
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Created: Thu, 12 Nov 2015, 15:28:19 EST by Prudence Mcrae on behalf of Scholarly Communication and Digitisation Service