The association between lung cancer incidence and ambient air pollution in China: a spatiotemporal analysis

Guo, Yuming, Zeng, Hongmei, Zheng, Rongshou, Li, Shanshan, Barnett, Adrian G., Zhang, Siwei, Zou, Xiaonong, Huxley, Rachel, Chen, Wanqing and Williams, Gail (2016) The association between lung cancer incidence and ambient air pollution in China: a spatiotemporal analysis. Environmental Research, 144 Part A: 60-65. doi:10.1016/j.envres.2015.11.004

Author Guo, Yuming
Zeng, Hongmei
Zheng, Rongshou
Li, Shanshan
Barnett, Adrian G.
Zhang, Siwei
Zou, Xiaonong
Huxley, Rachel
Chen, Wanqing
Williams, Gail
Title The association between lung cancer incidence and ambient air pollution in China: a spatiotemporal analysis
Journal name Environmental Research   Check publisher's open access policy
ISSN 0013-9351
Publication date 2016-01
Sub-type Article (original research)
DOI 10.1016/j.envres.2015.11.004
Open Access Status Not Open Access
Volume 144
Issue Part A
Start page 60
End page 65
Total pages 6
Place of publication Maryland Heights, MO, United States
Publisher Academic Press
Collection year 2017
Language eng
Formatted abstract
Background: China is experiencing more and more days of serious air pollution recently, and has the highest lung cancer burden in the world.

Objectives: To examine the associations between lung cancer incidence and fine particles (PM2.5) and ozone in China.

Methods: We used 75 communities’ data of lung cancer incidence from the National Cancer Registration of China from 1990 to 2009. The annual concentrations of fine particles (PM2.5) and ozone at 0.1° 0.1° spatial resolution were generated by combing remote sensing, global chemical transport models, and improvements in coverage of surface measurements. A spatial age period-cohort model was used to examine the relative risks of lung cancer incidence associated with the air pollutants, after adjusting for impacts of age, period, and birth cohort, sex, and community type (rural and urban) as well as the spatial variation on lung cancer incidence.

Results: The relative risks of lung cancer incidence related to a 10 mg/m3 increase in 2-year average PM2.5 were 1.055 (95% confidence interval (CI): 1.038, 1.072) for men, 1.149 (1.120, 1.178) for women, 1.060 (1.044, 1.075) for an urban communities, 1.037 (0.998, 1.078) for a rural population, 1.074 (1.052, 1.096) for people aged 30–65 years, and 1.111 (1.077, 1.146) for those aged over 75 years. Ozone also had a significant association with lung cancer incidence.

Conclusions: The increased risks of lung cancer incidence were associated with PM2.5 and ozone air pollution. Control measures to reduce air pollution would likely lower the future incidence of lung cancer.
Keyword Air pollution
Lung cancer incidence
Fine particles
Spatial age-period-cohort study
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Public Health Publications
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Created: Tue, 10 Nov 2015, 10:47:51 EST by Yuming Guo on behalf of School of Public Health