Glutamine supplementation in multiple trauma patients

Al Balushi, Ruqaiya M., Paratz, Jennifer D., Cohen, Jeremy and Banks, Merrilyn (2015). Glutamine supplementation in multiple trauma patients. In Rajkumar Rajendram, Victor R. Preedy and Vinood B. Patel (Ed.), Glutamine in Clinical Nutrition (pp. 181-194) New York, United States: Springer. doi:10.1007/978-1-4939-1932-1_14


Author Al Balushi, Ruqaiya M.
Paratz, Jennifer D.
Cohen, Jeremy
Banks, Merrilyn
Title of chapter Glutamine supplementation in multiple trauma patients
Title of book Glutamine in Clinical Nutrition
Place of Publication New York, United States
Publisher Springer
Publication Year 2015
Sub-type Research book chapter (original research)
DOI 10.1007/978-1-4939-1932-1_14
Open Access Status Not yet assessed
ISBN 9781493919321
9781493919314
Editor Rajkumar Rajendram
Victor R. Preedy
Vinood B. Patel
Chapter number 14
Start page 181
End page 194
Total pages 14
Total chapters 40
Collection year 2016
Language eng
Abstract/Summary During stress conditions such as multiple trauma and critical illness, the demand for glutamine increases and its concentration in plasma and muscle falls dramatically. Therefore, glutamine has been re-classified as an essential amino acid under such catabolic conditions. The role of glutamine supplementation in trauma patients has been extensively studies. Despite the numerous clinical trials that investigated the effect of enteral and parenteral glutamine supplementation in multiple trauma patients, the results are inconclusive. Glutamine supplementation through parenteral route has been associated with reduced infectious complications, mortality, costs and hospital length of stay. However, glutamine supplementation in multiple trauma patients receiving enteral nutrition and its best route are still controversial. Although glutamine supplementation is recommended in multiple trauma patients, large well designed multi-centre trials are required to provide a confirmed conclusion.
Keyword Multiple trauma
Head injury
Glutamine
Alanyl-glutamine
Supplementation
Enteral
Parenteral
Intravenous
Q-Index Code BX
Q-Index Status Confirmed Code
Institutional Status UQ

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