Building a BRIDGE for the integration of heterogeneous data from functional genomics into a platform for systems biology

Goesmann, Alexander, Linke, Burkhard, Rupp, Oliver, Krause, Lutz, Bartels, Daniela, Dondrup, Michael, McHardy, Alice C., Wilke, Andreas, Puehler, Alfred and Meyer, Folker (2003) Building a BRIDGE for the integration of heterogeneous data from functional genomics into a platform for systems biology. Journal of Biotechnology, 106 2-3: 157-167. doi:10.1016/j.jbiotec.2003.08.007


Author Goesmann, Alexander
Linke, Burkhard
Rupp, Oliver
Krause, Lutz
Bartels, Daniela
Dondrup, Michael
McHardy, Alice C.
Wilke, Andreas
Puehler, Alfred
Meyer, Folker
Title Building a BRIDGE for the integration of heterogeneous data from functional genomics into a platform for systems biology
Journal name Journal of Biotechnology   Check publisher's open access policy
ISSN 0168-1656
1873-4863
Publication date 2003-12-19
Sub-type Article (original research)
DOI 10.1016/j.jbiotec.2003.08.007
Open Access Status Not yet assessed
Volume 106
Issue 2-3
Start page 157
End page 167
Total pages 11
Place of publication Amsterdam, Netherlands
Publisher Elsevier BV
Language eng
Abstract The flood of data acquired from the increasing number of publicly available genomes has led to new demands for bioinformatics software. With the growing amount of information resulting from high throughput experiments new questions arise that often focus on the comparison of genes, genomes, and their expression profiles. Inferring new knowledge by combining different kinds of "post-genomics" data obviously necessitates the development of new approaches that allow the integration of variable data sources into a flexible framework. In this paper, we describe our concept for the integration of heterogeneous data into a platform for systems biology. We have implemented a Bioinformatics Resource for the Integration of heterogeneous Data from Genomic Explorations (BRIDGE) and illustrate the usability of our approach as a platform for systems biology for two sample applications.
Keyword Data integration
Genome annotation
Systems biology
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: UQ Diamantina Institute Publications
 
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