Emerging and novel therapeutic approaches in the treatment of male erectile dysfunction

Chung, Eric and Brock, Gerald B. (2011) Emerging and novel therapeutic approaches in the treatment of male erectile dysfunction. Current Urology Reports, 12 6: 432-443. doi:10.1007/s11934-011-0216-y


Author Chung, Eric
Brock, Gerald B.
Title Emerging and novel therapeutic approaches in the treatment of male erectile dysfunction
Journal name Current Urology Reports   Check publisher's open access policy
ISSN 1527-2737
1534-6285
Publication date 2011-12
Year available 2011
Sub-type Article (original research)
DOI 10.1007/s11934-011-0216-y
Open Access Status Not yet assessed
Volume 12
Issue 6
Start page 432
End page 443
Total pages 12
Place of publication Philadelphia, PA, United States
Publisher Springer Healthcare
Language eng
Abstract Over the past few decades, a dramatic increase in our understanding of the pathophysiology of penile erection has occurred. The advent of phosphodiesterase type 5 inhibitors has revolutionized the treatment of erectile dysfunction (ED), while the introduction of modern penile prosthesis has almost completely replaced the need for vascular surgery. Despite the efficacy of current therapeutic options for ED, they are not without limitations and remain insufficient to address the growing patient population and various underlying medical conditions. Newer and novel ED therapies aspire to treat underlying microvascular abnormalities, prevent cavernosal fibrosis, promote endothelial revascularization, modulate neurohormonal pathways, and regenerate new penile tissue.
Keyword Cell therapy
Erectile dysfunction
Gene therapy
Growth factors
Novel approaches
Penile prosthetic
Penile stent
Therapy
Tissue engineering
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Wed, 28 Oct 2015, 15:40:29 EST by Ms Kate Rowe on behalf of Learning and Research Services (UQ Library)