Recent advances in dengue pathogenesis and clinical management

Simmons, Cameron P., McPherson, Kirsty, Van Vinh Chau, Nguyen, Hoai Tam, D. T., Young, Paul, Mackenzie, Jason and Wills, Bridget (2015) Recent advances in dengue pathogenesis and clinical management. Vaccine, 33 50: 7061-7068. doi:10.1016/j.vaccine.2015.09.103


Author Simmons, Cameron P.
McPherson, Kirsty
Van Vinh Chau, Nguyen
Hoai Tam, D. T.
Young, Paul
Mackenzie, Jason
Wills, Bridget
Title Recent advances in dengue pathogenesis and clinical management
Journal name Vaccine   Check publisher's open access policy
ISSN 0264-410X
1873-2518
Publication date 2015
Year available 2015
Sub-type Article (original research)
DOI 10.1016/j.vaccine.2015.09.103
Open Access Status DOI
Volume 33
Issue 50
Start page 7061
End page 7068
Total pages 8
Place of publication London, United Kingdom
Publisher Elsevier
Collection year 2016
Language eng
Formatted abstract
This review describes and commentates on recent advances in the understanding of dengue pathogenesis and immunity, plus clinical research on vaccines and therapeutics. We expand specifically on the role of the dermis in dengue virus infection, the contribution of cellular and humoral immune responses to pathogenesis and immunity, NS1 and mechanisms of virus immune evasion. Additionally we review a series of therapeutic intervention trials for dengue, as well as recent clinical research aimed at improving clinical diagnosis, risk prediction and disease classification.
Keyword Clinical research
Dengue
Immunology
Pathogenesis
Vaccine
Virology
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Chemistry and Molecular Biosciences
 
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Citation counts: TR Web of Science Citation Count  Cited 6 times in Thomson Reuters Web of Science Article | Citations
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Created: Fri, 23 Oct 2015, 10:17:55 EST by Mrs Louise Nimwegen on behalf of School of Chemistry & Molecular Biosciences