T2-Weighted magnetic resonance imaging measurements of optic nerve sheath diameter in dogs with and without presumed intracranial hypertension

Scrivani, Peter V., Fletcher, Daniel J., Cooley, Stacy D., Rosenblatt, Alana J. and Erb, Hollis N. (2013) T2-Weighted magnetic resonance imaging measurements of optic nerve sheath diameter in dogs with and without presumed intracranial hypertension. Veterinary Radiology and Ultrasound, 54 3: 263-270. doi:10.1111/vru.12023


Author Scrivani, Peter V.
Fletcher, Daniel J.
Cooley, Stacy D.
Rosenblatt, Alana J.
Erb, Hollis N.
Title T2-Weighted magnetic resonance imaging measurements of optic nerve sheath diameter in dogs with and without presumed intracranial hypertension
Journal name Veterinary Radiology and Ultrasound   Check publisher's open access policy
ISSN 1058-8183
1740-8261
Publication date 2013
Year available 2013
Sub-type Article (original research)
DOI 10.1111/vru.12023
Open Access Status Not Open Access
Volume 54
Issue 3
Start page 263
End page 270
Total pages 8
Place of publication Hoboken, NJ United States
Publisher Blackwell Publishing
Language eng
Abstract Intracranial hypertension is a cause of cerebral ischemia and neurologic deficits in dogs. Goals of this retrospective study were to test interobserver agreement for MRI measurements of optic nerve sheath diameter and associations between optic nerve sheath diameter, signalment data, and presumed intracranial hypertension status in a cohort of dogs. A veterinary radiologist interpreted scans of 100 dogs and dogs were assigned to groups based on presence or absence of at least two MRI characteristics of presumed intracranial hypertension. Two observers who were unaware of group status independently measured optic nerve diameter from transverse T2-weighted sequences. Mean optic nerve sheath diameter for all dogs was 3 mm (1-4 mm). The mean difference between observers was 0.3 mm (limits of agreement, -0.4 and 1.0 mm). There was no correlation between optic nerve sheath diameter and age for either observer (r = -0.06 to 0.00) but a moderate positive correlation was observed between optic nerve sheath diameter and body weight for both observers (r = 0.70-0.76). The 22 dogs with presumed intracranial hypertension weighed less than the 78 dogs without (P = 0.02) and were more often female (P = 0.04). Dogs with presumed intracranial hypertension had a larger ratio of optic nerve sheath diameter to body weight for each observer-side pair (P = 0.01-0.04) than dogs without. Findings indicated that the ratio of MRI optic nerve sheath diameter relative to body weight may be a repeatable predictor of intracranial hypertension in dogs.
Keyword Dog
Intracranial pressure
MRI
Optic nerve sheath diameter
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Veterinary Science Publications
 
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Created: Mon, 19 Oct 2015, 18:24:13 EST by Alana Rosenblatt on behalf of School of Veterinary Science