Managing the difficult case of fetal anemia

Zhang, Eko G., Regan, Fiona, Layton, Mark, Paramasivam, Gowrishankar, Wyatt-ashmead, Jo, Roberts, Irene and Kumar, Sailesh (2011) Managing the difficult case of fetal anemia. Journal of Maternal-Fetal and Neonatal Medicine, 24 12: 1498-1503. doi:10.3109/14767058.2010.551149

Author Zhang, Eko G.
Regan, Fiona
Layton, Mark
Paramasivam, Gowrishankar
Wyatt-ashmead, Jo
Roberts, Irene
Kumar, Sailesh
Title Managing the difficult case of fetal anemia
Journal name Journal of Maternal-Fetal and Neonatal Medicine   Check publisher's open access policy
ISSN 1476-7058
Publication date 2011
Sub-type Article (original research)
DOI 10.3109/14767058.2010.551149
Open Access Status Not Open Access
Volume 24
Issue 12
Start page 1498
End page 1503
Total pages 6
Place of publication Oxfordshire United Kingdom
Publisher Taylor & Francis
Language eng
Formatted abstract
Objectives. To describe a series of complex fetal anemia cases, detail the appropriate investigations and management, and review the literature.

Methods. Four cases of non-red cell alloimmunization or infective cases of fetal anemia are presented.

Results. Of the four cases presented, one was a neonatal death, one pregnancy was terminated, one case was diagnosed with Diamond Blackfan anemia, and one case was due to recurrent feto-maternal hemorrhages despite negative Kleihauer tests.

Conclusions. Non-alloimmune causes of fetal anemia can be difficult to manage. Some cases require repeated and frequent intrauterine transfusions. The perinatal mortality and preterm delivery rates are increased, and some cases require considerable long-term treatment including regular transfusions. We present our experience of a series of non-immune fetal anemia managed in a tertiary unit, review the literature, and suggest appropriate management.
Keyword Fetal anemia
Fetal blood sampling
Non-immune hydrops
Red cell abnormalities
Feto-maternal hemorrhage
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
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