Sarcomatous carcinoma of the orbit: a case report and review of the literature

Mathew, Ninan, Mathew, Mathen and Farrah, Jon (2015) Sarcomatous carcinoma of the orbit: a case report and review of the literature. Case Reports in Ophthalmology, 6 180-185. doi:10.1159/000431282


Author Mathew, Ninan
Mathew, Mathen
Farrah, Jon
Title Sarcomatous carcinoma of the orbit: a case report and review of the literature
Journal name Case Reports in Ophthalmology   Check publisher's open access policy
ISSN 1663-2699
Publication date 2015-05-05
Sub-type Article (original research)
DOI 10.1159/000431282
Open Access Status DOI
Volume 6
Start page 180
End page 185
Total pages 6
Place of publication Basel, Switzerland
Publisher S. Karger AG
Collection year 2016
Language eng
Abstract Sarcomatous carcinomas (SCs) are rare tumours that contain malignant cells with epithelial and mesenchymal characteristics. SC rarely presents in the head and neck, and occurs even less often in the orbit. Only 8 cases of SCs located in the orbit or affecting the globe function have been described in the English literature. Here, we report a case of SC affecting the right orbit. SC is associated with a poor prognosis and advanced disease at presentation. Diagnosis is difficult, as histology often fails to definitively identify SC, necessitating a wide panel of molecular/immunological markers. Treatment options are generally aggressive but risky, and frequently yield poor results. Due to the rarity of SC, there has been little focus on the development of improved treatment options.
Keyword Carcinoma
Head and neck
Orbital
Sarcomatoid
Spindle cell tumours
Squamous
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Medicine Publications
 
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