Associations of Low- and High-Intensity Light Activity with Cardiometabolic Biomarkers

Howard, Bethany, Winkler, Elisabeth A.H., Sethi, Parneet, Carson, Valerie, Ridgers, Nicola D., Salmon, Jo, Healy, Genevieve N., Owen, Neville and Dunstan, David W. (2015) Associations of Low- and High-Intensity Light Activity with Cardiometabolic Biomarkers. Medicine and Science in Sports and Exercise, 47 10: 2093-2101. doi:10.1249/MSS.0000000000000631


Author Howard, Bethany
Winkler, Elisabeth A.H.
Sethi, Parneet
Carson, Valerie
Ridgers, Nicola D.
Salmon, Jo
Healy, Genevieve N.
Owen, Neville
Dunstan, David W.
Title Associations of Low- and High-Intensity Light Activity with Cardiometabolic Biomarkers
Journal name Medicine and Science in Sports and Exercise   Check publisher's open access policy
ISSN 1530-0315
0195-9131
Publication date 2015-10-01
Year available 2015
Sub-type Article (original research)
DOI 10.1249/MSS.0000000000000631
Open Access Status Not Open Access
Volume 47
Issue 10
Start page 2093
End page 2101
Total pages 9
Place of publication Philadelphia, Pennsylvania, United States
Publisher Lippincott Williams and Wilkins
Collection year 2016
Language eng
Formatted abstract
Purpose: Light-intensity physical activity (LIPA) accounts for much of adults’ waking hours ([almost equal to]40%) and substantially contributes to overall daily energy expenditure. Encompassing activity behaviors of low intensity (standing with little movement) to those of higher intensity (slow walking), LIPA is ubiquitous, yet little is known about how associations with health may vary depending on its intensity. We examined the associations of objectively assessed LIPA (categorized as either low LIPA [LLPA] or high LIPA [HLPA]) and moderate- to vigorous-intensity activity with cardiometabolic risk biomarkers.

Methods: Cardiometabolic biomarkers were measured in 4614 US adults (47 ± 17 yr) who participated in the 2003–2004 and 2005–2006 National Health and Nutrition Examination Survey cycles. Multiple linear regression analyses examined the associations of three accelerometer-derived physical activity (SD increment per day) intensity categories (LLPA, 100–761 counts per minute; HLPA, 762–1951 counts per minute; moderate-intensity physical activity [MPA], 1952–5724 counts per minute; vigorous-intensity physical activity [VPA], >=5725 counts per minute) with cardiometabolic biomarkers, adjusting for potential sociodemographic, behavioral, and medical confounders.

Results: All intensities of physical activity were beneficially associated with waist circumference, C-reactive protein, triglycerides, fasting insulin, [beta]-cell function, and insulin sensitivity (P < 0.05); only some activity intensities showed significant associations with systolic blood pressure (LLPA), body mass index, HDL cholesterol, fasting glucose, and 2-h plasma glucose (HLPA, MPA, and VPA). Generally, effect size increased with intensity of physical activity. Overall, further adjustment for waist circumference attenuated associations with MPA and VPA to a greater extent than associations with LLPA and HLPA.

Conclusions:
The cross-sectional findings provide novel evidence for the potential benefits of increasing both LLPA and HLPA. They further reinforce the established importance of moderate- to vigorous-intensity activity, the mainstay of public health recommendations.
Keyword ACCELEROMETER
POPULATION SURVEY
MOVEMENT
INCIDENTAL ACTIVITY
NHANES
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Public Health Publications
 
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