Average wild-type C57BL/6J mouse 3D MRI cortex labels

Egan, Gary F., Reutens, David, Galloway, Graham J., Watson, Charles, Andrew Janke, Kurniawan, Nyoman D. and Ullmann, Jeremy F. (2015): Average wild-type C57BL/6J mouse 3D MRI cortex labels. The University of Queensand. Dataset. doi:10.14264/uql.2015.865


Project name Australian Mouse Brain Mapping
Project description
We propose to establish the Australian Mouse Brain Mapping Consortium which is a national network of facilities allowing Australian researchers to better characterise mouse models of neurological diseases such as Alzheimer's Disease and stroke. Just as accurate maps were key to the voyages of geographic discovery in the 17th and 18th century, improved methods of mapping structural and functional changes in the brain of mouse models of neurological disease will be key to discovery in the neurosciences in the 21st century . For the Consortium the cartographic tools will be magnetic resonance imaging (MRI), microscopy and sophisticated computational methods of mapping brain structure and function. Participants in the Consortium are internationally recognised leaders in brain imaging based at Monash University, the Howard Florey Institute, the Prince of Wales Medical Research Institute and the Centre for Magnetic Resonance and the Queensland Brain Institute, University of Queensland.
Contact name Andrew Janke
Contact email a.janke1@uq.edu.au
Creator name Egan, Gary F.
Reutens, David
Galloway, Graham J.
Watson, Charles
Andrew Janke
Kurniawan, Nyoman D.
Ullmann, Jeremy F.
Creator(s) role Senior Researcher
Senior Researcher
Senior Researcher
Senior Researcher
Senior Researcher
Senior Researcher
Senior Researcher
Dataset name Average wild-type C57BL/6J mouse 3D MRI cortex labels
Dataset description
The neocortex is the largest component of the mammalian cerebral cortex. It integrates sensory inputs with experiences and memory, to produce sophisticated responses to an organisms internal and external environment. While areal patterning of the mouse neocortex has been mapped using histological techniques, the neocortex has not been comprehensively segmented in magnetic resonance images. This study presents a method for systematic segmentation of the C57BL/6J mouse neocortex. We created a minimum deformation atlas, which was placed into Waxholm space and has been hierarchically segmented into 74 neocortical and cortical-related regions, making it the most detailed atlas of the mouse neocortex currently available. In addition, we provide mean volumes and contrast intensities for each structure as well as a nomenclature comparison between the two most cited histological atlases of the mouse brain. This MR atlas is available for download, and it should enable researchers to perform automated segmentation in genetic models of cortical disorders.
Access conditions Open Access
Licencing and terms of access Creative Commons Attribution (only)

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ANZSRC Field of Research (FoR) Code 060805 Animal Neurobiology
1109 Neurosciences
110903 Central Nervous System
DOI 10.14264/uql.2015.865
Grant ID http://purl.org/au-research/grants/nhmrc/436673
Type of data MRI images
Language eng
Keyword Mouse brain mapping
Magnetic Resonance Imaging
Cortex
Collection type Dataset
Publisher The University of Queensand
Publication Year 2015
Copyright notice 2015, The University of Queensland
Additional Notes Whole data collection location: http://q0013-webdav.qcloud.qcif.edu.au/desktop.html?ds=2&plane=y&x=0.009&y=0.024&z=0.01&zoom=3

Document type: Data Collection
Collections: Research Data Collections
Centre for Advanced Imaging Publications
 
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Created: Fri, 25 Sep 2015, 13:42:33 EST by Fei Yu