Can different primary care databases produce comparable estimates of burden of disease: results of a study exploring venous leg ulceration

Petherick, Emily S ., Pickett, Kate E. and Cullum, Nicky A. (2015) Can different primary care databases produce comparable estimates of burden of disease: results of a study exploring venous leg ulceration. Family Practice, 32 4: 374-380. doi:10.1093/fampra/cmv013

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Author Petherick, Emily S .
Pickett, Kate E.
Cullum, Nicky A.
Title Can different primary care databases produce comparable estimates of burden of disease: results of a study exploring venous leg ulceration
Journal name Family Practice   Check publisher's open access policy
ISSN 0263-2136
1460-2229
Publication date 2015-05
Year available 2015
Sub-type Article (original research)
DOI 10.1093/fampra/cmv013
Open Access Status Not Open Access
Volume 32
Issue 4
Start page 374
End page 380
Total pages 7
Place of publication Oxford, United Kingdom
Publisher Oxford University Press
Collection year 2016
Language eng
Formatted abstract
Background. Primary care databases from the UK have been widely used to produce evidence on the epidemiology and health service usage of a wide range of conditions. To date there have been few evaluations of the comparability of estimates between different sources of these data.

Aim. To estimate the comparability of two widely used primary care databases, the Health Improvement Network Database (THIN) and the General Practice Research Database (GPRD) using venous leg ulceration as an exemplar condition.

Design of study. Cross prospective cohort comparison.

Setting. GPRD and the THIN databases using data from 1998 to 2006.

Method. A data set was extracted from both databases containing all cases of persons aged 20 years or greater with a database diagnosis of venous leg ulceration recorded in the databases for the period 1998-2006. Annual rates of incidence and prevalence of venous leg ulceration were calculated within each database and standardized to the European standard population and compared using standardized rate ratios.

Results. Comparable estimates of venous leg ulcer incidence from the GPRD and THIN databases could be obtained using data from 2000 to 2006 and of prevalence using data from 2001 to 2006.

Conclusions. Recent data collected by these two databases are more likely to produce comparable results of the burden venous leg ulceration. These results require confirmation in other disease areas to enable researchers to have confidence in the comparability of findings from these two widely used primary care research resources.
Keyword Epidemiology
Databases as topic
Incidence
Leg ulcers
Prevalence
Primary care
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2016 Collection
School of Nursing, Midwifery and Social Work Publications
 
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Created: Fri, 25 Sep 2015, 11:48:19 EST by Vicki Percival on behalf of School of Nursing, Midwifery and Social Work